Biology - Study Guide
Biology - Study Guide
8th Edition
ISBN: 9780321501561
Author: Martha R. Taylor
Publisher: PEARSON EDUCATION (COLLEGE)
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Chapter 11, Problem 5TYK

Which of the following is a key difference between GPCRs and RTKs?

  1. a. GPCRs use cGMP, but RTKs use cAMP.
  2. b. GPCRs are membrane bound, but RTKs are found in the cytoplasm.
  3. c. GPCRs are common in animal cells, but RTKs are common in plant cells.
  4. d. GPCRs generally activate a single pathway, but RTKs may trigger many signal transduction pathways.
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Scaffold proteins (a) release kinases and phosphatases into the extracellular fluid (b) bind G proteins to cell membranes (c) increase accuracy but slow signaling cascades (d) organize groups of intracellular signaling moleculesinto signaling complexes (e) are transcription factors found mainly in plant cells
For cellular transduction, why is it useful that phosphorylation cascades have a series of protein kinases?   a. they amplify the original signal       b. they always lead to the same cellular response   c.  the number of molecules used is small and fixed   d. they are cell specific
compare and contrast how GPCRs and RTKs transduce their signal to the cell? include the types of ligands they bind, the GTP binding protein that is activated, and how the signal is transduced and amplified. what effects does it have on the cell?
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