Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 11.4, Problem 1COMQ
DNA polymerase III is a processive enzyme, which means that
a. it does not dissociate from the growing strand after it has attached a
b. it makes a new strand very quickly.
c. it proceeds toward the opening of the replication fork.
d. it copies DNA with relatively few errors.
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What is DNA polymerase?
A. An enzyme that corrects mutations that arise during the replication of DNA
B. An enzyme that seals any gaps that remain between bases of replicating strands of DNA
C. Short, single strand of DNA that base-pairs with a specific DNA sequence
D. An enzyme that carries out DNA replication
DNA polymerase III is a processive enzyme, which means that
a. it does not dissociate from the growing strand after it has attached a nucleotide to the 3′ end.
b. it makes a new strand very quickly.
c. it proceeds toward the opening of the replication fork.
d. it copies DNA with relatively few errors.
In the dideoxy-sequencing reaction, what terminates DNA synthesis at a particular base? a. The absence of a base on the ddNTP halts the DNA polymerase. b. The ddNTP causes a break in the sugar–phosphate backbone. c. DNA polymerase will not incorporate a ddNTP into the growing DNA strand. d. The absence of a 3′-OH group on the ddNTP prevents the addition of another nucleotide.
Chapter 11 Solutions
Genetics: Analysis and Principles
Ch. 11.1 - 1. The complementarity of DNA strands is based on...Ch. 11.1 - 2. To make a new DNA strand, which of the...Ch. 11.1 - 3. The model that correctly describes the process...Ch. 11.2 - 1. A site in a chromosome where DNA replication...Ch. 11.2 - The origin of replication in E. coli contains a....Ch. 11.3 - 1. The enzyme known as ______ uses ________ and...Ch. 11.3 - In the lagging strand, DNA is made in the...Ch. 11.4 - 1. DNA polymerase III is a processive enzyme,...Ch. 11.4 - 2. The proofreading function of DNA polymerase...Ch. 11.5 - 1. In eukaryotes, DNA replication is initiated at...
Ch. 11.5 - 2. Which of the following statements regarding DNA...Ch. 11.5 - 3. In eukaryotes, RNA primers are primarily...Ch. 11.5 - 4. To synthesize DNA, what does telomerase use as...Ch. 11 - What key structural features of the DNA molecule...Ch. 11 - 2. With regard to DNA replication, define the term...Ch. 11 - Which of the following statements is not true?...Ch. 11 - The compound known as nitrous acid is a reactive...Ch. 11 - One way that bacterial cells regulate DNA...Ch. 11 - 6. The chromosome of E. coli contains 4.6 million...Ch. 11 - Here are two strands of DNA. DNA polymerase The...Ch. 11 - A DNA strand has the following sequence:...Ch. 11 - 9. List and briefly describe the three types of...Ch. 11 - 10. As shown in Figure 11.5, five DnaA boxes are...Ch. 11 - 11. Obtain two strings of different colors (e.g.,...Ch. 11 - Sometimes DNA polymerase makes a mistake, and the...Ch. 11 - 13. A short genetic sequence, which may be...Ch. 11 - Single-strand binding proteins keep the two...Ch. 11 - 15. In the following drawing, the top strand is...Ch. 11 - Describe the three important functions of DnaA...Ch. 11 - 17. Draw a picture that illustrates how DNA...Ch. 11 - What is an Okazaki fragment? In which strand of...Ch. 11 - Discuss the similarities and differences in the...Ch. 11 - 20. Explain the proofreading function of DNA...Ch. 11 - 21. What is a processive enzyme? Explain why...Ch. 11 - 22. What enzymatic features of DNA polymerase...Ch. 11 - 23. As shown in Figure 11.24, telomerase attaches...Ch. 11 - If a eukaryotic chromosome has 25 origins of...Ch. 11 - Prob. 25CONQCh. 11 - A diagram of a linear chromosome is shown here....Ch. 11 - As discussed in Chapter 18, some viruses contain...Ch. 11 - 28. Telomeres contain a 3′ overhang region, as...Ch. 11 - 1. Answer the following questions pertaining to...Ch. 11 - An absentminded researcher follows the steps of...Ch. 11 - Figure 11.4b shows an autoradiograph of a...Ch. 11 - 4. As described in Table 11.3, what is the...Ch. 11 - The technique of dideoxy sequencing of DNA is...Ch. 11 - 6. Another technique described in Chapter 21 is...Ch. 11 - The complementarity of its two strands is the...Ch. 11 - Compare and contrast DNA replication in bacteria...Ch. 11 - 3. DNA replication is fast, virtually error-free,...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- In DNA replication, a primer is _____. a. what the original DNA strands are called b. a molecule that provides the energy for nucleotide attachments c. a regulatory protein that turns on the gene that starts DNA replication d. an enzyme that breaks the hydrogen bonds between base pairs e. a short piece of nucleic acid that serves as an attachment point for DNA polymerasearrow_forwardDNA replication is said to be semiconservative because a. one of the new molecules conserves both of the original DNA strands. b. the new DNA molecule contains two new DNA strands. c. both of the new molecules contain one new strand and one old strand. d. DNA polymerase conserves both of the old strands.arrow_forwardBase analogs are mutagenic because of which characteristic? a. They produce changes in DNA polymerase that cause it to malfunction. b. They distort the structure of DNA. c. They are similar in structure to the normal bases. d. They chemically modify the normal bases.arrow_forward
- During DNA replication, the helicase enzyme binds to DNA and Select one: a. prevents the DNA strands from rewinding back into the helical shape b. cuts the double stranded DNA into single strands c. provides the starting point where new nucleotides can be added d. adds new nucleotides to the template strandarrow_forwardDNA polymerase adds nucleotides to Select one: a. the 5′ end, and the leading strand elongates in the 3′ to 5′ direction b. the 3′ end, and the leading strand elongates in the 5′ to 3′ direction c. the 5′ end, and the leading strand elongates in the 5′ to 3′ direction d. the 3′ end, and the leading strand elongates in the 3′ to 5′ directionarrow_forwardThe following diagram represents a DNA molecule that is undergoing replication. Draw in the strands of newly synthesized DNA and identify (a) the polarity of the newly synthesized strands, (b) the leading and lagging strands, (c) Okazaki fragments, and (d) RNA primers.arrow_forward
- Why is DNA replication considered semiconservative? A. Both strands of each replicating DNA molecules are conserved. B. One molecule consists of the old strands and the other DNA molecule is entirely new. C. One strand of each replicating DNA molecule is conserved and the other strand is newly synthesized. D. Both strands of each replicating DNA molecule are new.arrow_forwardWhen two adjacent bases in the same strand of DNA dimerize (form a covalent bond between them), what happens to the DNA? a. the original strand of DNA now contains a new DNA sequence b. the original strand of DNA is prevented from opening during replication, so this section of DNA will not be replicated c. the original strand of DNA is methylated, which causes the bases to mismatch d. the original strand of DNA is kinked, which prevents DNA polymerase from working properly e. the original strand of DNA is unaffected, so no additional mutations arisearrow_forwardWhat are major functions that DNA polymerase performs? A. unzips the DNA strand and makes the new nucleotides B. proof reads the new DNA strands for errors and corrects them C. bonds the nucleotides together forming the new DNA strand D. A, B, and C E. A and B F. B and C G. A and Carrow_forward
- DNA strands are anti-parallel and DNA polymerase can only synthesize DNA in a 5' to 3' direction. How does the enzyme synthesize both strands at the same time? A. The leading strand is sythesised in Okazaki fragments B. The lagging strand is synthesised in short Okazaki fragments. C. Only one strand is replicated. D. There are more than one DNA polymerase involved.arrow_forwardChose one of the options from A,B,C,D After replication,_________. a one new DNA double helix consists of two old strands and the other new DNA double helix consists of two new strands b each new DNA double helix consists of two new strands c each new DNA double helix consists of two old strands d each new DNA double helix consists of one old strand and one new strandarrow_forwardHow is each new nucleotide added to the growing end of a DNA strand? a. A dehydration reaction joins the monomer to the new strand b. By using DNA polymerase c. Both of the above d. A hydrolytic reaction joins the monomer to the new strandarrow_forward
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