Essentials of Human Anatomy and Physiology (Custom)
15th Edition
ISBN: 9781269752862
Author: Marieb
Publisher: PEARSON
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Textbook Question
Chapter 12, Problem 10MC
More than one choice may apply.
Which parts of an antibody molecule are different for an IgG antibody than for an IgM antibody that attacks the same antigen?
a. Heavy Chain constant region
b. Heavy chain variable region
c. Light chain constant region
d. Light chain variable region
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Which portion of an antibody provides antigen binding sites?
A.Heavy chain
B.Constant portion
C.Light chain
D.Variable portion
which one of the following properties of antibodies is NOT dependant on the structure of the heavy-chain constant region?
A. ability to cross the placenta
B. isotype (class of antibody)
C. ability to fix complement
D. affinity for drug
Which DOES NOT describe monoclonal antibodies?
Group of answer choices
a. Monoclonal antibodies are produced in test tubes by hybridoma cells
b. Monoclonal antibodies are specific to multiple antigens
c. These antibodies are used in diagnostic tests
d. The antibody producing cells may come from a non-human source
Chapter 12 Solutions
Essentials of Human Anatomy and Physiology (Custom)
Ch. 12 - Prob. 1MCCh. 12 - Prob. 2MCCh. 12 - Prob. 3MCCh. 12 - Which of the following are part of MALT? a....Ch. 12 - Prob. 5MCCh. 12 - Prob. 6MCCh. 12 - Chemical mediators of inflammation include a....Ch. 12 - Against which of the following will interferon do...Ch. 12 - Prob. 9MCCh. 12 - More than one choice may apply. Which parts of an...
Ch. 12 - Which of the following antibody capabilities...Ch. 12 - Prob. 12MCCh. 12 - Prob. 13MCCh. 12 - Prob. 14SAECh. 12 - Prob. 15SAECh. 12 - Prob. 16SAECh. 12 - Prob. 17SAECh. 12 - State the role and explain the importance of MALT.Ch. 12 - Prob. 19SAECh. 12 - Prob. 20SAECh. 12 - Prob. 21SAECh. 12 - Identify the four types of acquired Immunity....Ch. 12 - Prob. 23SAECh. 12 - Prob. 24SAECh. 12 - Binding of antigens to receptors of...Ch. 12 - Prob. 26SAECh. 12 - Prob. 27SAECh. 12 - 28. Compare and contrast a primary and a secondary...Ch. 12 - Prob. 29SAECh. 12 - Prob. 30SAECh. 12 - Prob. 31SAECh. 12 - Distinguish between immediate types of allergy and...Ch. 12 - Identify the four types of tissue grafts. In...Ch. 12 - Prob. 34SAECh. 12 - Prob. 35CAQCh. 12 - Prob. 36CAQCh. 12 - Prob. 37CAQCh. 12 - Mrs. Morrow, a 59-year-old woman, has undergone a...Ch. 12 - Prob. 39CAQCh. 12 - Capillary permeability increase and plasma...
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- A. In a table give three differences between antigen and antibodies B. Explain the structure of the antibody molecule C. Discuss the differences between humoral and cell mediated immunity in terms of chemicals and cells involved in each process as they tackle pathogens. You should write no more than 450 words.arrow_forwardDescribe how the B-cell receptor (BCR) differs from an antibody. Draw a generic example of each and point out the difference between them.arrow_forwardConstruct a typical antibody (immunoglobulin) molecule. Label the variable and constant regions, and the light and heavy chains. Indicate which region determines the antibody’s isotype (class). Indicate which region determines its antigenic specificity.arrow_forward
- Select the correct one. In antibody-mediated immunity, what happens immediately after B cells are activated? a. the foreign antigen-MHC complex is displayed on the cell surfaces. b. activated T helper cells interact with the B cells. c. the B cells are cloned. D. antibodies combine with antigens on the pathogen surface.arrow_forward(1) In antibody structure, where are can we find unique variable domains? A. at the tip of each polypeptide chain B. on the stem region of the antibody C. at the bottom of each polypeptide chain D. only on immunoglobulin E (2) The stem region of the antibody determines the: A. general immunological mechanism of action B. specific inflammatory response C. specific immunological mechnism of action D. shape of the variable domains (3) Antibodies are proteins that consists of ------ polypeptides in a ------ shaped structure. A. three, X B. four, Y C. five, clover D. two, Yarrow_forwardWould it be worse for the function of the antibody for it to lose the Fc region or a Fab region? Please explain your reasoning.arrow_forward
- Select all correct matches: a. Heavy chain / the larger of the two protein chain types found in antibodies b. Hapten / the site on an antibody that binds to antigen c. Gamma globulin / antibodies purified from serum d. Cytokine / a secreted protein that affects immune cell functionarrow_forwardWhich domain of antibody defines its type and which domain is for specificity against antigen. Also explain the rearrangement of genes for IgA.arrow_forwardWhy must antibody treatments like ZMapp be composed of monoclonal antibodies instead of polyclonal antibodies? a. Therapeutic antibodies must all bind the same epitope. b. Therapeutic antibodies must NOT all bind the same epitope. c. Monoclonal antibodies have much higher binding affinity than polyclonal antibodies. d. Monoclonal antibodies have much lower binding affinity than polyclonal antibodies. e. Monoclonal antibodies can be produced indefinitely; polyclonal antibodies can only be produced for a short time. IS it B? Can you please explainarrow_forward
- What is the predicted outcome if a patient receives an allogeneic hematopoietic cell transplant from a family member, and then receives a kidney transplant several months later from the same donor? a. Acute kidney rejection because the patient’s hematopoietic system has been fully reconstituted with patient-derived alloreactive T cells and NK cells. b. Graft-versus-host disease mediated by alloreactive T cells in the transplanted kidney. c. Secondary immune response by patient-derived memory T lymphocytes that were initially activated by the hematopoietic cell transplant. d. The patient is tolerant to alloantigens on the kidney graft and does not require long-term immunosuppressive drugs.arrow_forwardWhy is there an enzyme attached to the secondary antibody? a. They provide a colormetirc indication of antigen exposure b. They link to the proteins used c. They are used to detect DNAarrow_forwardSuppose a person recovers normally from viral infections, but then gets the same viral infections over and over again- unlike the rest of us. A. What is probably wrong –B cells, helper T cells and/or cytotoxic T cells? B. Should this person be at a higher risk of cancer than the rest of us? C. Should this person be able to lyse bacterial cells as well as the rest of us? D. Should this person tolerate a graft (from an unreated person) better than you are me?arrow_forward
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