Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Textbook Question
Chapter 12, Problem 19P
14CO2 was bubbled through a suspension of liver cells that was undergoing gluconeogenesis from lactate to glucose. Which carbons in the glucose molecule would become radioactive?
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14CO2 was bubbled through a suspension of liver cells that was undergoinggluconeogenesis from lactate to glucose. Which carbons in the glucose molecule would become radioactive?
Starting from glutamine, glycine, aspartate, N 10-formyi-THF, how many ATP- equivalents are required for purine nucleotide synthesis?
2
8
4
6
Lactate is a dead-end product in that its sole fate is to be converted back into glucose. Why then do cells bother to form lactate at all?
Chapter 12 Solutions
Biochemistry: Concepts and Connections (2nd Edition)
Ch. 12 - Prob. 1PCh. 12 - Methanol is highly toxic, not because of its own...Ch. 12 - Prob. 3PCh. 12 - Prob. 4PCh. 12 - Prob. 5PCh. 12 - Write balanced chemical equations for each of the...Ch. 12 - Prob. 7PCh. 12 - Prob. 8PCh. 12 - Prob. 9PCh. 12 - Prob. 10P
Ch. 12 - Some anaerobic bacteria use alternative pathways...Ch. 12 - Write a pathway leading from glucose to lactose in...Ch. 12 - Prob. 13PCh. 12 - Prob. 14PCh. 12 - Prob. 15PCh. 12 - How many ATP equivalents are consumed in the...Ch. 12 - Prob. 17PCh. 12 - Avidin is a protein that binds extremely tightly...Ch. 12 - 14CO2 was bubbled through a suspension of liver...Ch. 12 - Prob. 20PCh. 12 - Prob. 21PCh. 12 - Prob. 22PCh. 12 - Prob. 23PCh. 12 - 24. Glycogen synthesis and breakdown are regulated...Ch. 12 - Prob. 25PCh. 12 - Prob. 26PCh. 12 - Prob. 27PCh. 12 - Prob. 28PCh. 12 - 29 [1-14C] Ribose-5-phosphate is incubated with a...Ch. 12 - Prob. 30PCh. 12 - Prob. 31PCh. 12 - Prob. 32PCh. 12 - Prob. 33P
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- Starting from glutamine ,glycine, aspartate, N-10 formal-ThF ,how many ATP equivalents are required for purine synthesis?arrow_forwardHexokinase is an important enzyme in the metabolism of glucose. If theconcentration of hexokinase in our eukaryotic cell is 20 μM, how many glucose molecules are present per hexokinase molecule?arrow_forwardThe oxidation of 1 mol of glucose supplies enough metabolic energy to form 36 mol of ATP. Oxidation of 1 mol of a typical dietary fat like tristearin (C57H116O6) yields enough energy toform 458 mol of ATP. How many molecules of ATP can form per gram of (a) glucose; (b) tristearin?arrow_forward
- A glycogen polymer and an amylopectin polymer, each containing 100 monosaccharide subunits, are cleaved completely by an enzyme. How many individual glucose molecules are created during this process?arrow_forwardthe half life of metformin ( Glucophage) is 17.6 hours. What is the rate of decay?arrow_forwardSuppose you had separated the A and B chains of insulin by disulfide reduction. What chromatographic method should make it possible to isolate pure A and B chains? Explain your choice of separation method. You will findsome useful information in Tools of Biochemistry 5A.arrow_forward
- What intermediate in purine synthesis will accumulate if a strain of bacteria is lacking each of the following biochemicals? a. Aspartate b. Tetrahydrofolate c. Glycine d. Glutaminearrow_forwardMany studies that have revealed important biochemical processes in human beings, including those that underpin the development of new drugs, have been conducted in other organisms. These organisms include mammals such as mice and rats but also extend to single-celled organisms such as yeast. Why is this approach often productive?arrow_forwardCan you write possible mineralization and biotransformation reactions for glucose (C6H12O6) ?arrow_forward
- Part A. If you were to expose cells that are undergoing anaerobic respiration to a radioactive carbon isotope in the form of C6H12O6C6H12O6, which of the following molecules would you not expect to be radiolabeled? a)pyruvate b)succinyl CoA c)fructose-1,6-bisphosphate d)lactate Part b.If you were to expose cells that are undergoing aerobic respiration to a radioactive carbon isotope in the form of acetyl-CoA, which of the following molecules would you not expect to be radiolabeled? a)oxaloacetate b)succinyl CoA c)pyruvate d) CO2arrow_forwardThe enzyme phosphoglucomutase interconverts glucose-1-phosphate and glucose-6-phosphate. Why is this enzyme likely to include a side chain such as Ser in its active site?arrow_forwardWhy is the consumption of vitamin C as an antioxidant expected to donate its own electrons to free radicals?Explain the process and illustrate it, do it with physicochemical supportsarrow_forward
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