![EP INTRODUCTORY STATISTICS-MYSTATLAB](https://www.bartleby.com/isbn_cover_images/9780135190210/9780135190210_largeCoverImage.gif)
EP INTRODUCTORY STATISTICS-MYSTATLAB
3rd Edition
ISBN: 9780135190210
Author: Gould
Publisher: PEARSON CO
expand_more
expand_more
format_list_bulleted
Question
Chapter 12, Problem 58SE
a.
To determine
Calculate and compare the proportion of patients who experienced recurrence-free survival in the two groups.
b .
To determine
The hypothesis that a greater proportion of patients taking the drug experienced recurrence- free survival than those taking the placebo.
c.
To determine
Comment if the drug pembrolizumab may be effective in treating patients with advanced melanoma or not.
Expert Solution & Answer
![Check Mark](/static/check-mark.png)
Want to see the full answer?
Check out a sample textbook solution![Blurred answer](/static/blurred-answer.jpg)
Students have asked these similar questions
Prenatal vitamins and Autism. Researchers studying the link between prenatal vitamin use and autism surveyed the mothers of a random sample of children aged 24 - 60 months with autism and conducted another separate random sample for children with typical development. The table below shows the number of mothers in each group who did and did not use prenatal vitamins during the three months before pregnancy.
The May 10, 2007 issue of The New England Journal of Medicine describes two large randomized, placebo-controlled trials of a vaccine for HPV-related cancer. HPV is human papillomavirus, the most common form of sexually transmitted infection. For the group of people who received the vaccine, the HPV-related cancer rate was much lower than for those who received a placebo.
Which best describes the goal of this study?
A 2017 article in The New England Journal of Medicine details the results of a randomized clinical trial designed to evaluate the efficacy of a rotavirus gastroenteritis vaccine designed for infants. As per the authors:
“Each year, rotavirus gastroenteritis is responsible for about 37% of deaths from diarrhea among children younger than 5 years of age worldwide, with a disproportionate effect in sub-Saharan Africa. We conducted a randomized, placebo-controlled trial in Niger to evaluate the efficacy of a live, oral bovine rotavirus pentavalent vaccine (BRV-PV, Serum Institute of India) to prevent severe rotavirus gastroenteritis. Healthy infants received three doses of the vaccine or placebo at 6, 10, and 14 weeks of age. Episodes of rotavirus gastroenteritis were assessed through active and passive surveillance.”
The following Kaplan-Meier curves show the time to a diagnosis of rotavirus gastroenteritis separately for the vaccine and placebo samples. Infants were followed for up to 60…
Chapter 12 Solutions
EP INTRODUCTORY STATISTICS-MYSTATLAB
Ch. 12 - Dairy Products and Muscle The following two...Ch. 12 - Coffee and Depression The following two headlines...Ch. 12 - Marijuana Use and Bone Density In a 2017 study...Ch. 12 - Prob. 4SECh. 12 - Prob. 5SECh. 12 - Prob. 6SECh. 12 - Prob. 7SECh. 12 - Smoking Cessation In a 2018 study reported in The...Ch. 12 - Prob. 9SECh. 12 - Prob. 10SE
Ch. 12 - Prob. 11SECh. 12 - Sugary Drinks and Brain Health An April 2017...Ch. 12 - Expression of Feelings A 2017 Pew poll asked a...Ch. 12 - Prob. 14SECh. 12 - Prob. 15SECh. 12 - SAT Prep and Power Suppose an SAT tutoring company...Ch. 12 - Brain Games (Example 2) Researchers are interested...Ch. 12 - A Smile a Day Smiling is a sign of a good mood,...Ch. 12 - Speed Skating Suits (Example 3) Speed skating is a...Ch. 12 - Flu Vaccines and Age Suppose you want to compare...Ch. 12 - Preventing Heart Attacks with Aspirin Suppose that...Ch. 12 - Prob. 22SECh. 12 - Dietary Improvement and Depression In a 2017...Ch. 12 - Prob. 24SECh. 12 - Reading Colored Paper (Example 4) Some people...Ch. 12 - Prob. 26SECh. 12 - Prob. 27SECh. 12 - Prob. 28SECh. 12 - Prob. 29SECh. 12 - Library Audio Books Suppose a college is deciding...Ch. 12 - Prob. 31SECh. 12 - Prob. 32SECh. 12 - Prob. 33SECh. 12 - Prob. 34SECh. 12 - Prob. 35SECh. 12 - Prob. 36SECh. 12 - Prob. 37SECh. 12 - Prob. 38SECh. 12 - Prob. 39SECh. 12 - Prob. 40SECh. 12 - Prob. 41SECh. 12 - Prob. 42SECh. 12 - Prob. 43SECh. 12 - Prob. 44SECh. 12 - Yoga Study Design Refer to exercise 12.43. How...Ch. 12 - Fish Consumption Study Design Refer to exercise...Ch. 12 - Prob. 47SECh. 12 - Prob. 48SECh. 12 - Alumni Donations The alumni office wishes to...Ch. 12 - Prob. 50SECh. 12 - Prob. 51SECh. 12 - Prob. 52SECh. 12 - For exercises 12.51-12.53, evaluate the study...Ch. 12 - Prob. 54SECh. 12 - Anesthesia Care and Adverse Postoperative Outcomes...Ch. 12 - Prob. 56SECh. 12 - Prob. 57SECh. 12 - Prob. 58SE
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, statistics and related others by exploring similar questions and additional content below.Similar questions
- What is meant by the sample space of an experiment?arrow_forwardTreatment of patients whose injuries might cause massive blood loss has involved giving them plasma transfusions after they had been admitted to the emergency room. Sperry et al. (2018) investigated whether earlier treatment by the first responder might be more effective. In a randomized control trial, patients with trauma either did or did not receive earlier plasma transfusion. Of the 220 patients who received early plasma treatment, 52 died while of the 261 who received standard care, 89 died. Does the earlier treatment of plasma transfusion seem to be more effective? Standard Treatment 89 Early Treatment Died 52 Survived 167 173 What analysis is appropriate to run? heteroscedastic t-test Opaired t-test odds ratio O chi-squared goodness of fit homoscedastic t-testarrow_forward"Does ginkgo improve memory?" The law allows marketers of herbs and other natural substances to make health claims that are not supported by evidence. Brands of ginkgo extract claim to "improve memory and concentration." A randomized experiment found some statistically significant evidence for such effects. The subjects were 250 healthy volunteers over 65 years old. They were randomly assigned to take ginkgo or a placebo pill (a dummy pill that looks and tastes the same). All the subjects took a battery of tests for learning and memory before treatment started and again after six weeks. a). The article said the study was double-blind. What does this mean in the context of this study? Be very specific on who's being blinded and explain why they should be blinded. b). You suspect physical fitness and mental fitness go hand-in-hand. Create a flow chart to describe a design for an experiment to include the confounding variable physical fitness. Be very specific in your design. Include all…arrow_forward
- According to a research study, people are able to better manage their time when they wear watches than when they use mobile phones or other gadgets to keep track of time. To test this, 300 college students were randomized into a treatment group and a control group. The treatment group was asked to wear a watch every day, and the control group was asked to avoid wearing a watch for 50 days. The number of occasions when students from both groups arrived later than their scheduled time was noted. The results of the experiment showed that the mean score of the treatment group was exactly 15 points less than the mean score of the control group. To test whether the results could be explained by random chance, the researchers created the following table, which summarizes the results of 1,000 randomizations of the data with differences of means rounded to the nearest 5 points. Consider the significance level to be set at 5%, so results lower than 5% can be considered statistically significant.…arrow_forwardLung cancer is the leading cause of cancer‑related deaths in the United States. Researchers examined the idea of testing all Medicare‑enrolled heavy smokers for lung cancer with a computed tomography (CT) scan every year. In this population, the lifetime chance of developing lung cancer is high. In any given year, approximately 3%3% of heavy smokers develop lung cancer. The CT scan positively identifies lung cancer 89%89% of the time, and it gives a negative result for 93%93% of individuals who do not have lung cancer. (a) Use probability notation to express the three values cited. Match the notation with the appropriate values. Not necessarily all notation choices should be used.arrow_forwardIn an observational study it was found that people who had received the flu shot this year had better blood pressure readings, on average, than people who did not. Can it be claimed that the flu shot is the cause of the lower overall blood pressure? Why or why not?arrow_forward
- An investigator reviewed the medical records of 200 children seen for care at Boston Medical Center in the past year who were between the ages 8 and 12 and identified 40 children with asthma. He also identified 40 children of the same ages who were free of asthma. Each child and their family were interviewed to assess whether there might be an association between certain environmental factors such as exposure to second-hand smoke. This study is an example of a: Case-Control Study Crossover Trial Cohort Study Randomized Control Trialarrow_forwardMost cases of cervical cancer are linked to a few strains of the human papilloma virus (HPV). The pharmaceutical company Merck developed a vaccine (Gardisil) against these HPV strains. Worldwide clinical trials followed young women after vaccination or administration of placebo for two to four years for signs of HPV-caused cervical cancer. Based on a sample of 100 women in the Gardisil group, 34 % developed cervical cancer, and based on a sample of 100 women in the placebo group, 44 % developed cervical cancer. Test the claim that the proportion of women who developed cervical cancer in the Gardisil group is less than the proportion of women who developed cervical cancer in the placebo group at a = 0.05. Round your answers to three decimal places, and round any interim calculations to four decimal places. Fill in the hypotheses below where p₁ denotes the proportion of women who developed cervical cancer in the Gardisil group and p2 denotes the proportion of women who developed cervical…arrow_forwardMost cases of cervical cancer are linked to a few strains of the human papilloma virus (HPV). The pharmaceutical company Merck developed a vaccine (Gardisil) against these HPV strains. Worldwide clinical trials followed young women after vaccination or administration of placebo for two to four years for signs of HPV-caused cervical cancer. Based on a sample of 100 women in the Gardisil group, 34 % developed cervical cancer, and based on a sample of 100 women in the placebo group, 44% developed cervical cancer. Test the claim that the proportion of women who developed cervical cancer in the Gardisil group is less than the proportion of women who developed cervical cancer in the placebo group at a = 0.05. Round your answers to three decimal places, and round any interim calculations to four decimal places. Fill in the hypotheses below where p₁ denotes the proportion of women who developed cervical cancer in the Gardisil group and p2 denotes the proportion of women who developed cervical…arrow_forward
- A study investigated the joint effects of sleep quality and sleep duration on the development of coronary heart disease (CHD). A total of 60,586 individuals aged 40 and older with no current or prior history of CHD were enrolled into the study. A self-administered questionnaire was used to collect information on sleep quality and duration at the start of the study, and 43,910 participants reported getting ³6 hours of sleep per day. Participants were followed for approximately 12 years, for a total of 152,000 person-years among those getting <6 hours sleep/day and 527,000 person-years among those getting ³6 hours sleep/day. Out of 2,740 participants who developed CHD throughout follow-up, 721 participants reported getting <6 hours of sleep per day at baseline. Question 10: What is the incidence rate of coronary heart disease among all participants in the study?arrow_forwardMost cases of cervical cancer are linked to a few strains of the human papilloma virus (HPV). The pharmaceutical company Merck developed a vaccine (Gardisil) against these HPV strains. Worldwide clinical trials followed young women after vaccination or administration of placebo for two to four years for signs of HPV-caused cervical cancer. Based on a sample of 100 women in the Gardisil group, 24 % developed cervical cancer, and based on a sample of 100 women in the placebo group, 34 % developed cervical cancer. Test the claim that the proportion of women who developed cervical cancer in the Gardisil group is less than the proportion of women who developed cervical cancer in the placebo group at a = 0.10. Round your answers to three decimal places, and round any interim calculations to four decimal places. Fill in the hypotheses below where p₁ denotes the proportion of women who developed cervical cancer in the Gardisil group and p2 denotes the proportion of women who developed cervical…arrow_forwardA researcher randomly assigns participants to receive either a vaccine or a placebo, and number of infections are compared 4 weeks after the intervention. What type of design is this? Non-experimental design Experimental design ANOVA design Correlational designarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Holt Mcdougal Larson Pre-algebra: Student Edition...AlgebraISBN:9780547587776Author:HOLT MCDOUGALPublisher:HOLT MCDOUGALCollege Algebra (MindTap Course List)AlgebraISBN:9781305652231Author:R. David Gustafson, Jeff HughesPublisher:Cengage Learning
![Text book image](https://www.bartleby.com/isbn_cover_images/9780547587776/9780547587776_smallCoverImage.jpg)
Holt Mcdougal Larson Pre-algebra: Student Edition...
Algebra
ISBN:9780547587776
Author:HOLT MCDOUGAL
Publisher:HOLT MCDOUGAL
![Text book image](https://www.bartleby.com/isbn_cover_images/9781305652231/9781305652231_smallCoverImage.gif)
College Algebra (MindTap Course List)
Algebra
ISBN:9781305652231
Author:R. David Gustafson, Jeff Hughes
Publisher:Cengage Learning
![Text book image](https://www.bartleby.com/isbn_cover_images/9781938168383/9781938168383_smallCoverImage.gif)
Introduction to experimental design and analysis of variance (ANOVA); Author: Dr. Bharatendra Rai;https://www.youtube.com/watch?v=vSFo1MwLoxU;License: Standard YouTube License, CC-BY