Connect With Learnsmart Labs Online Access For Prescott's Microbiology
Connect With Learnsmart Labs Online Access For Prescott's Microbiology
11th Edition
ISBN: 9781260408997
Author: Joanne Willey
Publisher: Mcgraw-hill Higher Education (us)
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Chapter 12.5, Problem 1CC
Summary Introduction

Nitrogen is an important building block for cellular components such as amino acids and nucleic acids. Ammonia is a common source of nitrogen for many organisms. Ammonia assimilation is the process of releasing nitrogen from ammonia and utilizing it in the cell. Either the reductive amination or the glutamine synthetase-glutamate synthase system can be utilized to initially incorporate nitrogen into a carbon backbone.

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Why would glutamate utilize the oxidative deamination pathway over transamination – especially if removal of NH4+ requires ATP? Would it not be favorable for the body to just use transamination?
Which of the following statements about the transamination and deamination steps of amino acid degradation is true? (A) a-ketoglutarate is always formed during a transamination between an amino acid and glutamate. (B) Transamination reactions produce glutamate that is deaminated after entering the urea cycle. (C) Free ammonia is removed from glutamate using glutamate dehydrogenase and NAD+ as an oxidizing agent. (D) The free NH4+ that is removed from glutamate during the deamination reaction is used to form glucose.(E) The carbon backbone that results from transamination enters the mitochondria to be used in the urea cycle.
What is the physiological significance of the isozymic forms of lactate dehydrogenase (LDH)? Explain briefly.

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Connect With Learnsmart Labs Online Access For Prescott's Microbiology

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