MindTap Biology, 1 term (6 months) Printed Access Card for Starr/Taggart/Evers/Starr's Biology: The Unity and Diversity of Life (MindTap Course List)
MindTap Biology, 1 term (6 months) Printed Access Card for Starr/Taggart/Evers/Starr's Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN: 9781305269842
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 13, Problem 11GP

A single allele gives rise to the Hbs form of hemoglobin. Individuals who are homozygous for the allele (HbS/HbS) develop sickle-cell anemia (Section 9.6). Heterozygous individuals (HbA/HbS) have few symptoms. A couple who are both heterozygous for the HbS allele plan to have children. For each of the pregnancies, state the probability that they will have a child who is:

  • a. homozygous for the HbS allele
  • b. homozygous for the normal allele (HbA)
  • c. heterozygous: HbA/HbS
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Given that the normal hemoglobin allele (H) is dominant to the sickle-cell allele (h), each time two Hh individuals have a child together, what is the chance that the child will have sickle-cell disease? (a) 0% (b) 75% (c) 25% (d) 50% (e) 100%
The following is a summary of the possible sickle-cell genotypes and phenotypes: AA - cojmpletely normal AS - sickle-cell trait (this person has a combination of normal hemoglobin and the abnormal, sickled form of hemoglobin) SS - sickle-cell anemia (all abnormal hemoglobin)   Fill in the punnett square and answer the question: If both parents and heterozygous for sickle-cell disease, what are the possible genotypes and phenotypes for their children?
The following is a summary of the possible sickle-cell genotypes and phenotypes: AA - cojmpletely normal AS - sickle-cell trait (this person has a combination of normal hemoglobin and the abnormal, sickled form of hemoglobin) SS - sickle-cell anemia (all abnormal hemoglobin) Make a punnett square for help answering the question:  If both parents and heterozygous for sickle-cell disease, what are the possible genotypes and phenotypes for their children?
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