EBK ESSENTIALS OF GENETICS
9th Edition
ISBN: 8220102741614
Author: Palladino
Publisher: YUZU
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Chapter 13, Problem 11PDQ
Summary Introduction
To review:
The meaning of an inherited or a genetic disease on the basis of sickle cell anemia. The comparison between a genetic disease and a disease caused by the invasion of a microbe.
Introduction:
A disease in an organism is referred to as any sort of structural or functional disorder, which manifests itself in the form of symptoms. Diseases can be acute (short-lived), chronic (long-lived), or lifelong. The common reasons for disease occurrence area poorlifestyle, consumption of bad quality water, breathing in polluted air, and genetic makeup. Moreover, some diseases are common in certain geographical areas.
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Using sickle-cell anemia as an example, describe what is meant by a molecular or genetic disease. What are the similarities and dissimilarities between this type of a disorder and a disease caused by an invading microorganism?
What are Okazaki fragments? Why are they formed?
What type of mutation is sickle cell anemia? Explain the molecular basis of sickle cell anemia.
Chapter 13 Solutions
EBK ESSENTIALS OF GENETICS
Ch. 13 - CASE STUDY | Crippled ribosomes Diamond Blackfan...Ch. 13 - CASE STUDY | Crippled ribosomes Diamond Blackfan...Ch. 13 - Prob. 3CSCh. 13 -
HOW DO WE KNOW?
1. In this chapter, we focused on...Ch. 13 - Review the Chapter Concepts list on p. 238. These...Ch. 13 - List and describe the role of all molecular...Ch. 13 - Contrast the roles of tRNA and mRNA during...Ch. 13 - Francis Crick proposed the adaptor hypothesis for...Ch. 13 -
6. During translation, what molecule bears the...Ch. 13 - Summarize the steps involved in charging tRNAs...
Ch. 13 - Each transfer RNA requires at least four specific...Ch. 13 -
9. Explain why the one-gene:one-enzyme hypothesis...Ch. 13 - Prob. 10PDQCh. 13 - Prob. 11PDQCh. 13 - Prob. 12PDQCh. 13 - Assuming that each nucleotide is 0.34 nm long in...Ch. 13 - Review the concept of colinearity in Section 12.5...Ch. 13 -
15. In your opinion, which of the four levels of...Ch. 13 -
16. List and describe the function of as many...Ch. 13 - How does an enzyme function? Why are enzymes...Ch. 13 -
18. Shown in the following table are several...Ch. 13 -
19. Three independently assorting genes are known...Ch. 13 -
20. How would the results in cross (a) of Problem...Ch. 13 - A series of mutations in the bacterium Salmonella...Ch. 13 -
22. The emergence of antibiotic-resistant strains...
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- Explain briefly why the derivation of protein substitution matrices introduces a form of circular reasoning linked to the 'alignment paradox'arrow_forwardApproximately how many Okazaki fragments are synthesized in thereplication of the human genome?arrow_forwardWhich of the following (A through E ) would you expect to find in a nucleotide chain constructed for Sanger sequencing?arrow_forward
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- We need a string-matching-based approach to identifying protein homologies between several proteins. In what way does it function? With what evidence do you back up your assertion?arrow_forwardIf the mutation causing Tay Sachs disease involves a C to T change at position 4 in the sequence AAGCGTTAGCTAGGCC, what probe would you use to detect the mutation in individuals concerned about carrying the disease?arrow_forwardEstimate the time needed for E. coli RNA polymerase at 37 °C to transcribe the entire gene for a 50-kilodalton protein. What assumption or assumptions must be made for this estimate to be accurate?arrow_forward
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