GENETIC ANALYSIS: AN INTEG. APP. W/MAS
2nd Edition
ISBN: 9781323142790
Author: Sanders
Publisher: Pearson Custom Publishing
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Textbook Question
Chapter 13, Problem 19P
A boy with Down syndrome (trisomy
Explain how this is possible.
How many chromosomes do you expect to see in karyotypes of the parents?
What term best describes this kind of chromosome abnormality?
What is the probability the next child of this couple will have a normal phenotype and have
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A normal mother has translocations on chromosomes 14:21. With respect to chromosomes 14:21, how many combinations of chromosomes are possible? How many gametes are viable?
If the woman has children with an normal father, what is the probability that there is a daughter with Down Syndrome or a son with an unaffected phenotype?
A phenotypically normal woman has an abnormally structured chromosome 2, along with a normal homologue. She marries a phenotypically normal man with an abnormally structured chromosome 16 and a normal homologue. What is the probability of their child will have an abnormal chromosome 2 and 16? What is the probability that this child, having inherited both abnormal chromosomes, will now pass both abnormal chromosomes to its children?
Part of the karyotype of a diploid individual who is heterozygous for one chromosomal
rearrangement is shown in the diagram. The chromosomes involved in the rearrangement, and their
homologous pair, are shown. The location of each gene is labeled using horizontal lines and the
name of each gene is labeled using letters or numbers. Answer the following questions about the
diagram.
A. What rearrangement is shown? Be as specific as possible.
B. Describe a mutation scenario that could cause this rearrangement to be formed.
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Chapter 13 Solutions
GENETIC ANALYSIS: AN INTEG. APP. W/MAS
Ch. 13 - Prob. 1PCh. 13 - For one set of chromosomes carried by a triploid...Ch. 13 - 10.8 If the haploid number for a plant species is...Ch. 13 - From the following list, identify the types...Ch. 13 - Mating between a male donkey (2n=64) and a female...Ch. 13 - Prob. 6PCh. 13 - Prob. 7PCh. 13 - What can we conclude about a mutational event...Ch. 13 - 9. In terms of the chromosome content of nuclei,...Ch. 13 - 10. In Drosophila, an X-linked recessive allele...
Ch. 13 - The plants in this problem are the same as those...Ch. 13 - A normal chromosome and its homolog carrying a...Ch. 13 - 10.12 A pair of homologous chromosomes in...Ch. 13 - 10.13 An animal heterozygous for a reciprocal...Ch. 13 - Dr. Ara B. Dopsis has an idea he thinks will be a...Ch. 13 - Suppose polymerase chain reaction (PCR) is used...Ch. 13 - Prob. 17PCh. 13 - A healthy couple with a history of three previous...Ch. 13 - A boy with Down syndrome (trisomy 21) has 46...Ch. 13 - Prob. 20PCh. 13 - 10.28 A small population of deer living on an...Ch. 13 - In humans that XX/XO mosaics, the phenotype is...Ch. 13 - 10.20 A plant breeder would like to develop the...Ch. 13 - In Drosophilia, seven partial deletion (1to7)...Ch. 13 - Two experimental varieties of strawberry are...Ch. 13 - 10.23 In the tomato, Solanum esculentum, tall ()...Ch. 13 - In Drosophila, the wild-type red eye color is...Ch. 13 - A DrosophilaPelement 2.5kb in length is modified...Ch. 13 - A biologist studying flight mechanisms in insects...Ch. 13 - 30. After reading Experimental Insight and...Ch. 13 - 31. Two NotI restriction enzymes cleave DNA on...Ch. 13 - For the following crosses, determine as accurately...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Given the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the phenotype of this individual be?arrow_forwardImagine a germ cell for an animal that is 2n=4. Gene A and B are found on chromosome one, and the cell is homozygous for A(AA) and heterozygous for Bb. Gene D is found on chromosome 2 and the germ cell is heterozygous for the Allee of the gene (Dd). Meiosis for this germ cell results in the following four gametes, and one crossing over event during meiosis ABD, ABd, AbD, Abd. Draw the chromosomes in cell during metaphase of meiosis 1. Make sure to include chromosomes, the allele in the correct locations on the chromosomes AFTER the crossing over event, and spindle fibers.arrow_forwardFrom 2 to 6 percent of people with autism have an extra chromosome that consists of two long arms of chromosome 15. It includes two copies of the chromosome 15 centromere. Two normal copies of the chromosome are also present. What type of chromosome abnormality in a gamete can lead to this karyotype, which is called isodicentric 15?arrow_forward
- A boy with Down syndrome (trisomy 21) has 46 chromosomes. One parent and his two older sisters have a normal phenotype, but each have 45 chromosomes. a)Explain how this is possible. b)How many chromosomes do you expect to see in karyotypes of the parents? c)What term best describes this kind of chromosome abnormality? d)What is the probability the next child of this couple will have a normal phenotype and have 46 chromosomes? Explain your answer.arrow_forwardIn the fruit fly Drosophila melanogaster, a recessive condition called eyeless (ey) significantly interferes with normal eye development. Eyes are either very small or absent. The ey gene is found on chromosome 4, which is the smallest of the four chromosomes in the organism. Individuals with a single copy or three copies of chromosome 4 are viable and can reproduce. A trisomic wild-type male is crossed with a disomic wild-type female: see attached image Determine the chromosome constitution and phenotypic ratios in the offspring. Assume random segregation of chromosomes into gametes.arrow_forwardA phenotypically normal individual has the following combinations of normal and abnormal chromosomes:The normal chromosomes are shown on the left in each pair.Suggest a series of events (breaks, translocations, crossovers, etc.)that may have produced this combination of chromosomes.arrow_forward
- We say that genes that are close together on the same chromosome are linked. What does that mean? Imagine that in a diploid nucleus, one chromosome has the allele R and right next to it on the same chromosome is the allele T for a different gene. Are these linked? Imagine that r is right next to t on the homologous chromosome. If this cell never undergoes meiosis, does this matter at all? If it does undergo meiosis, what are the two genotypes that the gametes are most likely to have? Look at Figure for help if you need it.arrow_forwardDraw a Punnett square for the dihybrid cross. There are two known alleles of gene occupying a specific locus in the X chromosome. The gene in question codes for a transcription factor involved in digit development. The mutant allele is dominant and gives rise to an additional but non-functioning little finger (polydactyly) on both hands. A couple have had their DNA sequenced at the region of interest, the male exhibits polydactyly because of the mutation, the female is homozygous wild type at the same locus and therefore has the wild type phenotype. Both have green eyes. In this story; eye colour shows a monogenic autosomal inheritance pattern and the allele for brown eyes shows incomplete dominance with that for blue eyes, the heterozygote phenotype is green eyes. The genes for eye colour and polydactyly show no linkage.arrow_forwardExplain how an individual can have Down's Syndrome, and a karyotype that reveals 46 chromosomes. Group of answer choices The individual has an inversion on chromosome 21. The individual is trisomic for chromosome 21. The individual has one chromosome that is the result of a translocation. The individual is monosomic for chromosome 21. None of these is correct.arrow_forward
- A woman with no phenotype is known to have a 14:21 translocation. Please answer questions 1 and 2. 1. With respect to only chromosomes 14 and 21, how many distinct chromosome combinations will happen in her eggs? What portion will be viable? 2. If she has children with a normal man (no translocations), what is the probability that they have a daughter with Down Syndrome or a son with no phenotype?arrow_forwardIn a sample of 1000 patients with Down syndrome, a geneticist discovers that 95% of them are trisomic, while 5% have diploid number of chromosomes. Explain this discrepancy.arrow_forwardGiven the following genetic map, predict the chance an offspring would inherit the exact same haplotypes that the parents had. Assume interference in this area of the chromosome is 5%. Please report your value as a percent (%). A |-- 3 mu -- |-- 12 mu -- | Parent 1 Haplotypes: A1 B6 C14/A5 B1 C3 Parent 2 Haplotypes: A8 B3 C2 / A7 B2 C5arrow_forward
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