WORLD OF CELL+MASTERING ACCESS >CUSTOM
9th Edition
ISBN: 9781323445044
Author: Hardin
Publisher: PEARSON C
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Chapter 13, Problem 1Q
How could you use paclitaxel, which makes MTs less likely than normal to depolymerize, to study whether the completion of mitosis requires disassembly of MTs?
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Chapter 13 Solutions
WORLD OF CELL+MASTERING ACCESS >CUSTOM
Ch. 13 - Cytoskeletal polymers are modular, and their...Ch. 13 - How could you use paclitaxel, which makes MTs less...Ch. 13 - The amount of dynamic instability exhibited by...Ch. 13 - Prob. 13.3CCCh. 13 - In which of the following cells would you expect...Ch. 13 - Filaments and Tubules. Indicate whether each of...Ch. 13 - True or False. Identify each of the following...Ch. 13 - Prob. 13.3PSCh. 13 - Stabilization and the Critical Concentration....Ch. 13 - Prob. 13.5PS
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Hoechst 33258 is a chemical dye that binds specifically to DNA in live cells, and when excited by UV light, it fluoresces in the visible spectrum. Name and describe one specific method, employing Hoechst 33258, an investigator would use to isolate fibroblasts in the G2 phase of the cell cycle from those fibroblasts in interphase.arrow_forwardWhat is the name of the structure that the microtubules bind to during mitosis?arrow_forwardBiologists have long been interested in the effects of radiation on cells. In one experiment, researchers examined the effect of radium on mitosis of chick embryo cells growing in culture. A population of experimental cells was examined under the microscope for the number of cells in telophase (as a measure of mitosis occurring) before, during, and after exposure to radium. The results are shown in the Figure. What is the effect of radium exposure on mitosis? Source: R. G. Canti and M. Donaldson. 1926. The effect of radium on mitosis in vitro. Proceedings of the Royal Society of London, Series B, Containing Papers of a Biological Character 100:413419.arrow_forward
- Rb is a negative regulator that blocks the cell cycle at the G1 checkpoint until the cell achieves a requisite size. What molecular mechanism does Rb employ to halt the cell cycle?arrow_forwardIf 17 Beta estradiol can diffuse through cell membranes, explain why all cell types are not sensitive to the presence of 17 beta estradiol?arrow_forwardOne change observed at the centrosomes early in mitosis is an increase in the number of γ-TURCcomplexes (which contain γ-tubulin.).How does the presence of γ-tubulin affect the balance between microtubule assembly & disassembly? Why might having more of it present in the centrosomal region be beneficial in the spindle assembly process?arrow_forward
- Many of the cell’s hydrolytic enzymes are located in the lysosome, where the pH is ∼5. What would you expect to be the optimum pH for these enzymes, and why would this protect the rest of the cell from the destructive power of these enzymes upon the accidental rupture of a lysosome?arrow_forwardIn the absence of cdc25 cells would not be able to undergo mitosis. True or False?arrow_forwardwhat are mitophagy protein complex and what are they do?arrow_forward
- In which phase of the cell cycle does hydroxyurea produce its main effect?arrow_forwardThe lifetime of a microtubule in a mammalian cell, between its formation by polymerization and its spontaneous disappearance by depolymerization, varies with the stage of the cell cycle. For an actively proliferating cell, the average lifetime is 5 minutes in interphase and 15 seconds in mitosis. If the average length of a microtubule in interphase is 20 μm, how long will it be during mitosis, assuming that the rates of microtubule elongation due to the addition of tubulin subunits in the two phases are the same?arrow_forwardHow did you know that Paclitaxel was inhibiting cell division? What method of observation was used and how did you interpret the images to come to your conclusion that Paclitaxel was inhibiting cell division?arrow_forward
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