BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
9th Edition
ISBN: 9781319425784
Author: BERG
Publisher: Macmillan Higher Education
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Chapter 13, Problem 6P
Interpretation Introduction
Interpretation:
The mechanism of
Concept introduction:
ATPases belong to the class of enzymes catalyzing the ATP to ADP decomposition. This also results in the formation of a free phosphate ion. The reverse reaction is also catalyzed by the same enzyme. The energy is released during the dephosphorylation reaction. The process is widely used in all the forms of life.
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Question 17
If you completely inhibit the Na+/K+ ATPase, which of the following would you most likely observe?
Decrease in Na+/Ca++ exchanger activity
The Nernst potential for K+ would become more positive
Intracellular Na+ concentration would increase
All of the above
Fo-F1 ATPase. The energy for ATP synthesis from ADP and Pi is provided by the downhill transport of protons through the rotary FoF1 ATP synthase . The enzyme has 3 alpha-beta and 12 ‘c’ subunits. The mitochondrion maintains change in membrane potential=180 mV (negative inside), pHin = 8, pHout=7, [Pi] = 3 mM and ADP is present as well.
. What [ATP]/[ADP] ratio will be established at steady-state under these conditions?
What would be the [ATP]/[ADP] ratio if the enzyme had only 9 ‘c’ subunits? full revolution of the crank (gamma subunit) produces 3 ATP.
Calculation about delta standard G, delta H, detla S. Question attached as photo below. And my answer attempted. Need my answer verified and corrected if neccesary. Please let me know where I got wrong and what key ideas I had miss. Thanks.
Chapter 13 Solutions
BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
Ch. 13 - Prob. 1PCh. 13 - Prob. 2PCh. 13 - Prob. 3PCh. 13 - Prob. 4PCh. 13 - Prob. 5PCh. 13 - Prob. 6PCh. 13 - Prob. 7PCh. 13 - Prob. 8PCh. 13 - Prob. 9PCh. 13 - Prob. 10P
Ch. 13 - Prob. 11PCh. 13 - Prob. 12PCh. 13 - Prob. 13PCh. 13 - Prob. 14PCh. 13 - Prob. 15PCh. 13 - Prob. 16PCh. 13 - Prob. 17PCh. 13 - Prob. 18PCh. 13 - Prob. 19PCh. 13 - Prob. 20PCh. 13 - Prob. 21PCh. 13 - Prob. 22PCh. 13 - Prob. 23PCh. 13 - Prob. 24PCh. 13 - Prob. 25PCh. 13 - Prob. 26PCh. 13 - Prob. 27PCh. 13 - Prob. 28PCh. 13 - Prob. 29PCh. 13 - Prob. 30PCh. 13 - Prob. 31PCh. 13 - Prob. 32P
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- Reductive power. What ratio of NADPH to NADP+ is required to sustain [GSH] = 10 mM and [GSSG] = 1 mM ? Use the redox potentials given in Table 18.1 .arrow_forwardFo-F1 ATPase. The energy for ATP synthesis from ADP and Pi is provided by the downhill transport of protons through the rotary FoF1 ATP synthase (lecture 22). The enzyme has 3 a-b and 12 ‘c’ subunits. The mitochondrion maintains Df=180 mV (negative inside), pHin = 8, pHout=7, [Pi] = 3 mM and ADP is present as well. How much energy is available (from the proton electrochemical gradient) for ATP synthesis under these conditions (in kJ/mol)? What [ATP]/[ADP] ratio will be established at steady-state under these conditions? What would be the [ATP]/[ADP] ratio if the enzyme had only 9 ‘c’ subunits? Remember that full revolution of the crank (gamma subunit) produces 3 ATP.arrow_forwardFrog poison. Batrachotoxin (BTX) is a steroidal alkaloid from the skin of Phyllobates terribilis, a poisonous Colombian frog (the source of the poison used on blowgun darts). In the presence of BTX, Na+Na* channels in an excised patch stay persistently open when the membrane is depolarized. They close when the membrane is repolarized. Which transition is blocked by BTX?arrow_forward
- Hi, can you help me, please?and give an explanation for the answer.arrow_forwardIn full details. Explain the significance of redox potentials formed by redox pairs in the electron transport chain.arrow_forwardTrue or False. The steroid hormone estradiol (estrogen) readily crosses membranes by simple diffusion but the much smaller H+ requires transport proteins. Explain your answer.arrow_forward
- Only a few. Why do only a small number of sodium ions need to flow through the Na+Na* channel to change the membrane potential significantly?arrow_forwardPlease ASAP. Thank you. The figure below shows that after the application of ouabain, the rest potential approaches 0 mV. Which of the following is the most likely explanation for this observation.arrow_forwardPlease ASAP. Thank you.arrow_forward
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