The mechanism for the formation of the diol has to be given and has to indicate the 18 O in the diol product. Concept Introduction: The reactions of Epoxides with strong nucleophiles requires a strong driving force that helps in the removal of ring strain associated with the three-membered ring of an Epoxide. These ring opening reactions also occur under acidic conditions. When the epoxide is unsymmetrical, the nucleophile attacks at the more substituted position of the protonated epoxide ring. The mechanism of acid-catalyzed ring opening of an Epoxide occurs in two steps. In first step, the protonation of Epoxide occurs. In second step, the attack of nucleophile occurs in the protonated Epoxide by S N 2 process.

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Answer 1

Question

Chapter 13.10, Problem 19ATS

Interpretation Introduction

Interpretation: The mechanism for the formation of the diol has to be given and has to indicate the 18O in the diol product.

Concept Introduction:

The reactions of Epoxides with strong nucleophiles requires a strong driving force that helps in the removal of ring strain associated with the three-membered ring of an Epoxide. These ring opening reactions also occur under acidic conditions.

When the epoxide is unsymmetrical, the nucleophile attacks at the more substituted position of the protonated epoxide ring.

The mechanism of acid-catalyzed ring opening of an Epoxide occurs in two steps.

In first step, the protonation of Epoxide occurs.

In second step, the attack of nucleophile occurs in the protonated Epoxide by SN2 process.

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Answer 2

Question

Chapter 13.10, Problem 19ATS

Interpretation Introduction

Interpretation: The mechanism for the formation of the diol has to be given and has to indicate the 18O in the diol product.

Concept Introduction:

The reactions of Epoxides with strong nucleophiles requires a strong driving force that helps in the removal of ring strain associated with the three-membered ring of an Epoxide. These ring opening reactions also occur under acidic conditions.

When the epoxide is unsymmetrical, the nucleophile attacks at the more substituted position of the protonated epoxide ring.

The mechanism of acid-catalyzed ring opening of an Epoxide occurs in two steps.

In first step, the protonation of Epoxide occurs.

In second step, the attack of nucleophile occurs in the protonated Epoxide by SN2 process.

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Answer 3

Question

Chapter 13.10, Problem 19ATS

Interpretation Introduction

Interpretation: The mechanism for the formation of the diol has to be given and has to indicate the 18O in the diol product.

Concept Introduction:

The reactions of Epoxides with strong nucleophiles requires a strong driving force that helps in the removal of ring strain associated with the three-membered ring of an Epoxide. These ring opening reactions also occur under acidic conditions.

When the epoxide is unsymmetrical, the nucleophile attacks at the more substituted position of the protonated epoxide ring.

The mechanism of acid-catalyzed ring opening of an Epoxide occurs in two steps.

In first step, the protonation of Epoxide occurs.

In second step, the attack of nucleophile occurs in the protonated Epoxide by SN2 process.

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Answer 4

Question

Chapter 13.10, Problem 19ATS

Interpretation Introduction

Interpretation: The mechanism for the formation of the diol has to be given and has to indicate the 18O in the diol product.

Concept Introduction:

The reactions of Epoxides with strong nucleophiles requires a strong driving force that helps in the removal of ring strain associated with the three-membered ring of an Epoxide. These ring opening reactions also occur under acidic conditions.

When the epoxide is unsymmetrical, the nucleophile attacks at the more substituted position of the protonated epoxide ring.

The mechanism of acid-catalyzed ring opening of an Epoxide occurs in two steps.

In first step, the protonation of Epoxide occurs.

In second step, the attack of nucleophile occurs in the protonated Epoxide by SN2 process.

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Answer 5

Chapter 13.10, Problem 19ATS

Interpretation Introduction

Interpretation: The mechanism for the formation of the diol has to be given and has to indicate the 18O in the diol product.

Concept Introduction:

The reactions of Epoxides with strong nucleophiles requires a strong driving force that helps in the removal of ring strain associated with the three-membered ring of an Epoxide. These ring opening reactions also occur under acidic conditions.

When the epoxide is unsymmetrical, the nucleophile attacks at the more substituted position of the protonated epoxide ring.

The mechanism of acid-catalyzed ring opening of an Epoxide occurs in two steps.

In first step, the protonation of Epoxide occurs.

In second step, the attack of nucleophile occurs in the protonated Epoxide by SN2 process.

Answer 6

Chapter 13.10, Problem 19ATS

Interpretation Introduction

Interpretation: The mechanism for the formation of the diol has to be given and has to indicate the 18O in the diol product.

Concept Introduction:

The reactions of Epoxides with strong nucleophiles requires a strong driving force that helps in the removal of ring strain associated with the three-membered ring of an Epoxide. These ring opening reactions also occur under acidic conditions.

When the epoxide is unsymmetrical, the nucleophile attacks at the more substituted position of the protonated epoxide ring.

The mechanism of acid-catalyzed ring opening of an Epoxide occurs in two steps.

In first step, the protonation of Epoxide occurs.

In second step, the attack of nucleophile occurs in the protonated Epoxide by SN2 process.

Answer 7

Chapter 13.10, Problem 19ATS

Interpretation Introduction

Interpretation: The mechanism for the formation of the diol has to be given and has to indicate the 18O in the diol product.

Concept Introduction:

The reactions of Epoxides with strong nucleophiles requires a strong driving force that helps in the removal of ring strain associated with the three-membered ring of an Epoxide. These ring opening reactions also occur under acidic conditions.

When the epoxide is unsymmetrical, the nucleophile attacks at the more substituted position of the protonated epoxide ring.

The mechanism of acid-catalyzed ring opening of an Epoxide occurs in two steps.

In first step, the protonation of Epoxide occurs.

In second step, the attack of nucleophile occurs in the protonated Epoxide by SN2 process.

Answer 8

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Answer 9

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Answer 10

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Answer 11

Ch. 13.2 - Prob. 1LTS Ch. 13.2 - Prob. 1PTS Ch. 13.2 - Prob. 2PTS Ch. 13.2 - Prob. 3ATS Ch. 13.4 - Prob. 4CC Ch. 13.5 - Prob. 2LTS Ch. 13.5 - PRACTICE the skill Show reagents that you could...Ch. 13.5 - APPLY the skill Compound 2 was made as a...Ch. 13.5 - Prob. 7CC Ch. 13.5 - Prob. 8CC

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