Prescott's Microbiology
11th Edition
ISBN: 9781260211887
Author: WILLEY, Sandman, Wood
Publisher: McGraw Hill
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Textbook Question
Chapter 14, Problem 1AL
Attenuation affects anabolic pathways, whereas repression affects either anabolic or catabolic pathways. Provide an explanation for this.
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Explain how catabolite repression depends on an activatorprotein
Explain why (a) inactivation of the O2 or O3 sequence of the lac operon causes only a twofold loss in repression, and (b) inactivation of both O2 and O3 reduces repression ∼70-fold.
What is diauxic growth? Explain how catabolite repression causes diauxic growth.
Chapter 14 Solutions
Prescott's Microbiology
Ch. 14.2 - MICRO INQUIRY In what way is on inducer molecule...Ch. 14.2 - MICRO INQUIRY Is allolactose a corepressor or...Ch. 14.2 - Retrieve, Infer, Apply Many genes and operons are...Ch. 14.2 - Prob. 2CCCh. 14.2 - Prob. 3CCCh. 14.3 - MICRO INQUIRY How does this attenuation respond to...Ch. 14.4 - MICRO INQUIRY How does inhibition of translation...Ch. 14.4 - Prob. 1CCCh. 14.4 - Prob. 2CCCh. 14.4 - Prob. 3CC
Ch. 14.4 - Retrieve, Infer, Apply How are translational...Ch. 14.4 - Prob. 5CCCh. 14.5 - MICRO INQUIRY Relative to each promoter, where...Ch. 14.5 - MICRO INQUIRY For what other compounds would you...Ch. 14.5 - Prob. 1CCCh. 14.5 - Retrieve, Infer, Apply What is diauxic growth?...Ch. 14.5 - Retrieve, Infer, Apply Describe the events that...Ch. 14.5 - Retrieve, Infer, Apply E. coli has two phosphate...Ch. 14.5 - Prob. 5CCCh. 14.6 - Prob. 1MICh. 14.6 - MICRO INQUIRY Why does V. harveyi make three...Ch. 14.6 - Prob. 3MICh. 14.6 - Prob. 1CCCh. 14.6 - Prob. 2CCCh. 14.6 - Prob. 3CCCh. 14.6 - Retrieve, Infer, Apply Why might bacteria use...Ch. 14.6 - Prob. 5CCCh. 14.6 - Prob. 6CCCh. 14 - Prob. 1RCCh. 14 - Prob. 2RCCh. 14 - Prob. 3RCCh. 14 - Prob. 4RCCh. 14 - Attenuation affects anabolic pathways, whereas...Ch. 14 - Describe the phenotype of the following E. coli...Ch. 14 - Prob. 3ALCh. 14 - What would be the phenotype of a B. subtilis...Ch. 14 - Propose a mechanism by which a cell might sense...Ch. 14 - Prob. 6ALCh. 14 - Prob. 7ALCh. 14 - Prob. 8ALCh. 14 - Prob. 9AL
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- Explain why inactivation of the O1 sequence of the lac operator almost completely abolishes repression of the lac operon.arrow_forwardCan you explain in technical detail how global control mechanisms of catabolite repression work? Thank Youarrow_forwardWhat is known as catabolite repression ?arrow_forward
- Discuss genetic evidence that lacI encodes an allostericrepressor protein that binds the operator DNA.arrow_forwardDescribe the mechanism by which cAMP receptorprotein (CRP), the regulatory protein for catabolite repression, functions. Use the lactose operon as an example.arrow_forwardRepressors are inactivated either by interaction with a small-molecule inducer or by proteolytic cleavage. Why is it advantageous for a repressor like the lac repressor to be inactivated by binding to allolactose rather than by proteolytic cleavage?arrow_forward
- When cAMP binds to the Catabolite Activator Protein (CAP), it causes a conformational change on the protein, which results in binding to the CAP-binding site on the DNA and ___________________________ of the lac operon. This conformational change induced by the binding of another molecule is known as a(n) _________________________________. transcription repression; binding effect translation; distortion effect mutation; interactive effect attenuation; compression effect transcription activation; allosteric effectarrow_forwardExplain the role/importance of the localization of GTPase-activating protein (Ran-GAP) in BOTH nuclear export and import. What would occur if there was a loss of function mutation in Ran-GAP? What would occur if Ran-GAP was localized in the nucleus?arrow_forwardThe TRP operon functions by attenuation. Briefly explain how attenuation works and why it is necessary, in addition to the repressor protein, in regulating the operon.arrow_forward
- If the binding activity was purified, suggest two experimental approaches that could be taken to verify that this factor is in fact a transcription factor? Explain.arrow_forwardThe concentration of DnaK increases after a heat shock, yet its effects on sigma-32 activity are very negative. How could the increase in a protein that inhibits the activity of sigma-32 lead to an increase in the transcription of heat shock proteins?arrow_forwardCTP synthetase is allosterically activated by GTP. What function might this play in the cell?arrow_forward
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