Concept explainers
MAKE CONNECTIONS Ø The gene that causes sickle-cell disease is present in a higher percentage of residents of sub-Saharan Africa than among those of African descent living in the United States. Even though this gene causes sickle-cell disease, it also provides some protection from malaria, a serious disease that is widespread in sub-Saharan Africa but absent in the United States. Discuss an evolutionary process that could account for the different percentages of the sickle-cell gene among residents of the two regions. (See Concept 1.2.)
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Chapter 1 Solutions
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- If 9% of an African population is born with a severe form of sickle-cell anemia (ss), what percentage of the population will be more resistant to malaria because they are heterozygous (Ss) for the sickle-cell gene? Assume Hardy-Weinberg conditions. Submit your answer as it is. a) homozygous recessive individuals (q²) b) the recessive allele (q) c) the dominant allele (p) d) homozygous dominant individuals (p²) e) heterozygous individuals (2pq)arrow_forwardJust as anatomical homology can lead to vestigial structuressuch as human wisdom teeth and the wings of flightlessbirds, genetic homology can lead to vestigial DNA sequences.For example, most mammal species produce an enzyme,L-gulonolactone oxidase, that catalyzes the last step in the productionof vitamin C. The species that produce the enzyme areable to do so because they all inherited the gene that encodesit from a common ancestor. Humans, however, do not produceL-gulonolactone oxidase, so we can’t produce vitamin C ourselvesand must consume it in our diets. But even though wedon’t produce the enzyme, our cells do contain a stretch of DNAwith a sequence very similar to that of the enzyme-producinggene present in rats and most other mammals. The human version,though, does not encode the enzyme (or any protein). Weinherited this stretch of DNA from an ancestor that we share withother mammal species, but in us, the sequence has undergonea change that rendered it nonfunctional. (The…arrow_forward2a)An ancient gene underwent duplication during the course of evolution to yield two chain genes designated as δ and ε genes. What is the name of A,B,C and the contrast between B and C.arrow_forward
- Asian tiger mosquito Trace its origin and evolutionary history or changes in the species. Describe its structures and their functions. What is the importance of this species to our environment? Give trivia about this species. Does this organism produce oxygen? Explain. What are the ancestral species of your chosen organism? Has this species been genetically engineered? If yes, in what way? How does this species reproduce? What organisms have similar structures to this species? Do these structures have the same function? Does the species have tissues, organs, and/or organ systems? What is its role in the flow of energy? Give at 15 least a sentence to each question.arrow_forwardWhat is the difference between a neutral and an adaptive evolutionary process? Describe two or more examples of each. At the molecular level, explain how mutations can be neutral or adaptive.arrow_forwardWhich of the following proteins is thought to have been the first to evolve from an ancestral gene duplication of the most ancient O2 transporting protein in vertebrate hemoglobin (found today in all vertebrates except the agnathan fishes)? A. gamma-globin (-globin) B. epsilon-globin (-globin) C. alpha-globin (-globin) D. delta-globin (-globin) E. zeta-globin (-globin)arrow_forward
- 2b)An ancient gene underwent duplication during the course of evolution to yield two chain genes designated as δ and ε genes. Jessica’s final year project deals with the metagenomic studies of anfH homologous genes from freshwater lake samples in Kampar Eastlake. She successfully cloned and sequenced two partial anfH homologous gene sequences.BlastX analyses revealed that one of the DNA sequences showed highestsimilarity to AnfH protein from a Brazilian soil bacteria isolate while the second sequence showed highest identity to the AnfH protein sequence of a bacterium that was isolated from Tonle Sap, a freshwater lake in Cambodia. To determine their evolutionary relationship, she subsequently constructed a phylogenetic tree using the corresponding protein sequences. Describe the steps that are required toperform the analysis.arrow_forwardEvolution in Humans 1) explain what evolutionary mechanisms are involved in creating variation in populations 2) define homology and analogy and discuss examples of eacharrow_forwardPLEASE ANSWER THE QUESTION AND EXPLAIN SUCCINTLY IN 2 SENTENCESarrow_forward
- MAKE CONNECTIONS In a region free of malaria, would individuals who areheterozygous for the sickle-cell allele be selected for or selected against? Explain.arrow_forwardOnce nuclear DNA sequencing became fast and able to handle sequencing ancient DNA, living humans were found to have some Neanderthal genes. Is this finding clear evidence that some early modern humans did indeed hybridize with Neanderthals? Why?arrow_forwardIf myoglobin is found in all chordates, urochordates, and cephalochordates, b-globin is found in all vertebrates, a-globin in all ostracoderm descendants, z-globin in all gnathostomes, e-globin in all viviparous mammals, and d-globin in all eutherian mammals, then the most recent globin gene must be: myoglobin, found only in descendants of the chordates, urochordates, and cephalochordates zeta-globin (z-globin), found only in descendants of the ancestral gnathostome fishes epsilon-globin (e-globin), found only in descendants of the ancestral marsupials beta-globin (b-globin), found only in descendants of the ancestral vertebrates delta-globin (g-globin), found only in descendants of the ancestral eutheriansarrow_forward
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