Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 14.2, Problem 2COMQ
The binding of _______ to lac repressor causes lac repressor to _______ to the operator site, thereby _______ transcription.
a. glucose, bind, inhibiting
b. allolactose, bind, inhibiting
c. glucose, not bind, increasing
d. allolactose, not bind, increasing
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In the presence of allolactose, the lac repressor
a. binds to the operator.
b. binds to the promoter.
c. cannot bind to the operator.
d. binds to the regulator gene.
Which protein(s) would be bound to the DNA of the lac operon in the presence of both lactose and glucose?
A.) both lac repressor protein AND CRP-cAMP
B.)neither the lac repressor protein NOR CRP-cAMP
C.)the lac repressor protein
D.)CRP-cAMP
What is the difference between the core promoter and the regulatory promoter?
a. Only the core promoter has consensus sequences.
b. The regulatory promoter is farther upstream of the gene.
c. General transcription factors bind to the core promoter; transcriptional activator proteins bind to the regulatory promoter.
d. Both b and c.
Chapter 14 Solutions
Genetics: Analysis and Principles
Ch. 14.1 - 1. A repressor is a __________ that _________...Ch. 14.1 - 2. Which of the following combinations will cause...Ch. 14.2 - 1. What is an operon?
a. A site in the DNA where...Ch. 14.2 - The binding of _______ to lac repressor causes lac...Ch. 14.2 - Prob. 3COMQCh. 14.2 - How does exposing an E. coli cell to glucose...Ch. 14.3 - When tryptophan binds to trp repressor, this...Ch. 14.3 - During attenuation, when tryptophan levels are...Ch. 14.3 - Operons involved with the biosynthesis of...Ch. 14.4 - 1. Translation can be regulated by
a....
Ch. 14.4 - Prob. 2COMQCh. 14.5 - 1. For a riboswitch that controls transcription,...Ch. 14 - 1. What is the difference between a constitutive...Ch. 14 - In general, why is it important to regulate genes?...Ch. 14 - Prob. 3CONQCh. 14 - Transcriptional regulation often involves a...Ch. 14 - An operon is repressible-a small effector molecule...Ch. 14 - Prob. 6CONQCh. 14 - 7. What is enzyme adaptation? From a genetic point...Ch. 14 - Prob. 8CONQCh. 14 - Prob. 9CONQCh. 14 - Prob. 10CONQCh. 14 - Mutations may have an effect on the expression of...Ch. 14 - 12. Would a mutation that inactivated lac...Ch. 14 - Prob. 13CONQCh. 14 - 14. As shown in Figure 14.12, four regions within...Ch. 14 - 15. As described in Chapter 13, enzymes known as...Ch. 14 - 16. The combination of a 3–4 stem-loop and a...Ch. 14 - 17. Mutations in tRNA genes can create tRNAs that...Ch. 14 - Prob. 18CONQCh. 14 - Prob. 19CONQCh. 14 - A species of bacteria can synthesize the amino...Ch. 14 - 21. Using three examples, describe how allosteric...Ch. 14 - How are the actions of lac repressor and trp...Ch. 14 - 23. Transcriptional repressor proteins (e.g., lac...Ch. 14 - Answer the following questions that pertain to the...Ch. 14 - Chapter 21 describes a blotting method known as...Ch. 14 - As described in experimental question E2 and also...Ch. 14 - Prob. 4EQCh. 14 - Explain how the data shown in Figure 14.9 indicate...Ch. 14 - Prob. 6EQCh. 14 - Lets suppose you have isolated a mutant strain of...Ch. 14 - Prob. 1QSDCCh. 14 - Prob. 2QSDC
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- Can one transcription factor sometimes act as a repressor and sometimes act as an activator? a. Yes, but it depends on where the transcription factor binds in the promoter b. Yes, but it depends on other proteins that might act with the transcription factor c. No, transcription factors are always either activators or repressors d. Yes, but only if a mutation happensarrow_forwardThe lactose operon is likely to be transcribed when _____. A) there is more glucose in the cell than lactose B) there is glucose but no lactose in the cell C) the cAMP level is high and the lactose level is low D) the cyclic AMP and lactose levels are both high within the cellarrow_forwardWhich will be bound to the Lac Operon in an environment with lactose and glucose? A) both repressor and CAP B) repressor only C) CAP only D) neither repressor nor CAParrow_forward
- In the lac operon, the lac genes are transcribed in the presence of lactose because a RNA polymerase binds to the operator b The repressor can not bind the promoter c Production of the repressor protein is inducible d The inducer binds to the repressor e The inducer binds to the operatorarrow_forwardWhich of the following does not accurately describe eukaryotic transcriptional factors? a. Changes in transcriptional factor express can lead to changes in development. b. Most can regulate multiple different genes. c. They are each specific to one gene. d. Expression of different transcription factors leads to differentiation of cells.arrow_forwardWhich of the following is true of transcription factors? A)The same transcription factors are found in all cell types. B)They can increase or decrease gene expression. C)They are a type of cis-acting element. D)They bind only to promoters.arrow_forward
- What is the effect of a mutation in the allosteric site of the Lac Repressor protein? A) The Lac Operon would always be expressed whenever glucose is absent. B) The Lac Operon would never be expressed in any environment. C) The Lac Operon would be regulated normally. D) The Lac Operon would be never be expressed in lactose but would always be expressed in glucose.arrow_forwardPredict the effects of deleting the following regions of DNA: (a) The gene encoding lac repressor (b) The lac operator (c) The gene encoding CAParrow_forwardA mutation occurs in the lac operon operator site such that LacI can no longer bind to the operator site. The effect that this mutation has on the cell is that a. the activity of the lac operon will not be affected. b. the cell can no longer convert lactose to glucose. c. the expression of the lac genes cannot be turned off. d. the expression of the lac genes cannot be turned on.arrow_forward
- A mutation that inactivates the repressor gene of the lac operon results in (a) the continuous transcription of the structural genes (b) no transcription of the structural genes (c) the binding of the repressor to the operator (d) no production of RNA polymerase (e) no difference in the rate of transcriptionarrow_forwardA mutation occurs in a gene, resulting in it being expressed at the wrong time during development. Where is the mutation most likely to be found? a) In the transcription start site (TSS) b) In a TF binding site in the cis-regulatory region c) In the coding sequence d) In the 5' UTRarrow_forwardIs each of the following statements true or false? A. An enhancer is a type of regulatory element. B. A core promoter is a type of regulatory element. C. Regulatory transcription factors bind to regulatory elements. D. An enhancer may cause the down regulation of transcription.arrow_forward
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