Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Textbook Question
Chapter 14.3, Problem 12CC
A drug that blocks all Ca2+ channels in the myocardial contractile cell membrane is placed in the solution around the cell. What happens to the force of contraction in that cell?
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Compare and contrast the action potential of a myocardial conductive cell and the action potential of a myocardial contractile cell.
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d-leaky Na+ channels
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Chapter 14 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 14.1 - A cardiovascular system has what three major...Ch. 14.1 - What is the difference between (a) the pulmonary...Ch. 14.2 - Which is more important for determining flow...Ch. 14.2 - The two identical tubes below have the pressures...Ch. 14.2 - All four tubes below have the same driving...Ch. 14.2 - Two canals in Amsterdam are identical in size, but...Ch. 14.3 - What prevents electrical signals from passing...Ch. 14.3 - Prob. 8CCCh. 14.3 - Prob. 9CCCh. 14.3 - Compare the receptors and channels involved in...
Ch. 14.3 - If a myocardial contractile cell is placed in...Ch. 14.3 - A drug that blocks all Ca2+ channels in the...Ch. 14.3 - Which ions moving in what directions cause the...Ch. 14.3 - At the molecular level, what is happening during...Ch. 14.3 - Lidocaine is a molecule that blocks the action of...Ch. 14.3 - What does increasing K+ permeability do to the...Ch. 14.3 - A new cardiac drug called ivabradine selectively...Ch. 14.3 - Do you think that the Ca2+ channels in...Ch. 14.3 - What happens to the action potential of a...Ch. 14.3 - In an experiment, the vagus nerve, which carries...Ch. 14.4 - Name two functions of the AV node. What is the...Ch. 14.4 - Prob. 22CCCh. 14.4 - Occasionally an ectopic pacemaker {ktopos, out of...Ch. 14.4 - Prob. 24CCCh. 14.4 - Which chamberatrium or ventriclehas higher...Ch. 14.4 - Prob. 26CCCh. 14.4 - Prob. 27CCCh. 14.4 - Prob. 28CCCh. 14.4 - Prob. 29CCCh. 14.4 - Why does ventricular pressure shoot up suddenly at...Ch. 14.4 - Prob. 31CCCh. 14.4 - Prob. 32CCCh. 14.4 - A persons aortic valve opening has become...Ch. 14 - What contributions to understanding the...Ch. 14 - List three functions of the cardiovascular system.Ch. 14 - Prob. 3RQCh. 14 - Prob. 4RQCh. 14 - Prob. 5RQCh. 14 - Prob. 6RQCh. 14 - Prob. 7RQCh. 14 - Distinguish between the two members of each of the...Ch. 14 - Prob. 9RQCh. 14 - Prob. 10RQCh. 14 - What is the proper term for each of the following?...Ch. 14 - List the events of the cardiac cycle in sequence,...Ch. 14 - Prob. 13RQCh. 14 - Compare and contrast the structure of a cardiac...Ch. 14 - Prob. 15RQCh. 14 - Correlate the waves of an ECG with mechanical...Ch. 14 - Prob. 17RQCh. 14 - List and briefly explain four types of information...Ch. 14 - Define inotropic effect. Name two drugs that have...Ch. 14 - Prob. 20RQCh. 14 - Police Captain Jeffers has suffered a myocardial...Ch. 14 - Prob. 22RQCh. 14 - Prob. 23RQCh. 14 - Police Captain Jeffers in question 21 has an...Ch. 14 - Prob. 25RQCh. 14 - Prob. 26RQCh. 14 - Prob. 27RQCh. 14 - A person has a total blood volume of 5 L. Of this...
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- The entry of calcium into a ventricular muscle cell helps to maintain depolarization of the membrane during the plateau phase of the action potential, but this calcium also performs what other function?arrow_forwardMitral valve prolapse is a disease where the valve between the left atrium and left ventricle doesn’t close completely. What effect would this have on the movement of blood through the heart?arrow_forwardFill in the blank: The fibers that carry cardiac impulses from the interventricular septum into the myocardium are called_______________________.arrow_forward
- Describe why a doctor would give a patient that is diagnosed with acute myocardial infarction the treatment of tissue plasminogen activator(tPA)? What will it do?arrow_forwardAll of the following are correct about the isovolumetric contraction, except ____________. A. This phase of the cardiac cycle begins with the appearance of the QRS complex of the ECG, which represents atrial repolarization and ventricular depolarization B. It represents the time period between the closure of the AV valves and the opening of the aortic and pulmonic valves, ventricular pressure rises rapidly without a change in ventricular volume C. The rate of pressure increase in the ventricles is determined by the rate of contraction of the muscle fibers, which is determine by mechanisms governing excitation-contraction coupling D. Ventricular chamber geometry changes considerably as the heart becomes more spheroid in shape; circumference increases and atrial base-to-apex length increasesarrow_forwardDescribe the pacemaker potential and the myocardial action potential, and explain how the latter correlates with myocardial contraction and relaxation.arrow_forward
- We analyzed the difference between the action potential of a cardiac contractile cell and an action potential in a neuron. Describe the physiological mechanisms behind the primary difference in the shape of these two action potentials. Why is this feature important to the normal workings of the heart?arrow_forwardWhat is the consequence of the prolonged plateau of depolarization in ventricular myocytes? a-it causes ventricular myocytes to contract for a longer time, allowing the ventricles time to empty b-it gives additional time for the atria to contract, filling the ventricles more completely c-it causes repolarization to be delayed which slows heart rate d-it allows the ventricles a moment to rest before completing contractionarrow_forwardAn area of dead myocardial tissue is called.....arrow_forward
- In the initial stages of ventricular fibrillation (during which the heart produces no functional contraction), tissue perfusion in the heart actually increases. Explain.arrow_forwardAll of the following are part of the cardiac conduction system except the: a. chordae tendineae b. Purkinje fibers c. sinoatrial node d. atrioventricular bundlearrow_forward
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