GENETIC ANALYSIS: AN INTEG. APP. W/MAS
2nd Edition
ISBN: 9781323142790
Author: Sanders
Publisher: Pearson Custom Publishing
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Textbook Question
Chapter 15, Problem 10P
The term heterochromatin refers to heavily condensed regions of chromosomes that are largely devoid of genes. Since few genes exist in those regions, they almost never decondense for transcription. At what point during the cell cycle would you expect to observe the decondensation of heterochromatic regions? Why?
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The interphase is the part of the eukaryotic cell cycle that is most transcriptionally active. Gene regulation during this phase involves changes in the chromatin.
a) What is chromatin?
b) How can the chromatin structure change?
Consider the figure beow, which depicts chromatin within the neucleus of a eukaryotic cell.
nucleus
O The letter A indicates regions of a single chromosome which are not expressed, and the letter B indicates
regions of a single chromosome which are expressed.
O Both answer choice A and answer choice B are correct.
The letter A indicates regions of a single chromosome which are condensed and attached to the nuclear
lamina, and the letter B indicates regions of a single chromosome which are partially decondensed.
O Answer choices A, B and C are all correct.
O The letter A represents repressed TADS, and the letter B represents active TADS.
The picture below depicts electron micrographs of the major levels of chromatin structure. Match each of the listed conditions with the most likely levels of chromatin structure under that condition.
Chapter 15 Solutions
GENETIC ANALYSIS: AN INTEG. APP. W/MAS
Ch. 15 - 13.1 Devoting a few sentences to each, describes...Ch. 15 - 13.2 Describe and give an example (real or...Ch. 15 - What is meant by the term chromatin remodeling?...Ch. 15 - 13.4 What general role does acetylation of histone...Ch. 15 - 13.5 Describe the roles of writers, readers, and...Ch. 15 - Outline the roles of RNA in eukaryotic gene...Ch. 15 - 13.7 What are the roles of the Polycomb and...Ch. 15 - Most biologists argue that the regulation of gene...Ch. 15 - Compare and contrast the transcriptional...Ch. 15 - The term heterochromatin refers to heavily...
Ch. 15 - 13.11 Compare and contrast promoters and enhancers...Ch. 15 - 13.12 What are the different chromatin...Ch. 15 - 13.13 Define epigenetics, and provide examples...Ch. 15 - What is one proposed role for lncRNAs?Ch. 15 - 13.17 A hereditary disease is inherited as an...Ch. 15 - Prob. 16PCh. 15 - A gene expressed in long muscle of the mouse is...Ch. 15 - The consequences of four deletions from the region...Ch. 15 - Provide a description of the mechanistic roles of...Ch. 15 - 13.20 A muscle enzyme called ME is produced by...Ch. 15 - 21. A muscle protein in mouse is produced through...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What is chromatin condensation?arrow_forwardDuplication of chromatin material takes place in which phase?arrow_forwardOne change observed at the centrosomes early in mitosis is an increase in the number of γ-TURCcomplexes (which contain γ-tubulin.).How does the presence of γ-tubulin affect the balance between microtubule assembly & disassembly? Why might having more of it present in the centrosomal region be beneficial in the spindle assembly process?arrow_forward
- In which phases of the cell cycle would you expect double-strand break repair and nonhomologous end joining to occur and why?arrow_forwardWhich of the following represents the order of increasingly higher levels of organization of chromatin? Select one: O a. looped domain, nucleosome, 30-nm chromatin fiber O b. 30-nm chromatin fiber, nucleosome, looped domain C. nucleosome, looped domain, 30-nm chromatin fiber O d. looped domain, 30-nm chromatin fiber, nucleosome nucleosome, 30-nm chromatin fiber, looped domain е.arrow_forwardDefine the following terms: a. chromosome b. chromatinarrow_forward
- How can the chromatin structure change?arrow_forward(a)Discuss or explain the consequences for a cell if the chromatin could not be remodeled. (b) Does the action of the telemorase enzyme contradict the central dogma of molecular biology? why or why not?arrow_forwardIn the tracking chromosomal DNA movement through mitosis experiment, how many chromosomes did each of your daughter cells contain? Why is it important for each daughter cell to contain information identical to the parent cell? How often do human skin cells divide? Why might that be? Compare this rate to how frequently human neurons divide. What do you notice?arrow_forward
- If the chromatin is removed from a eukaryotic nucleus, what remains?arrow_forwardWhen chromatin is treated with non-specific nucleases, what is the length of the resulting pieces of DNAarrow_forwardIn eukaryotic cells, the DNA is tightly packed in the form of chromatin. His- tones are positively charged proteins. Negatively charged DNA wraps tightly around these proteins to form nucleosomes. Additionally, there are other mechanisms for the compaction of chromatin. (a) Which histone(s) are critical for higher-order chromatin structure? (b) What are the non-histone proteins responsible for structural maintenance of chromosomes? (c) To initiate transcription, compact DNA must partially unwind. Explain the role of histones in this process. (d) Micrococcal nuclease can cleaves DNA at sites where it can access DNA without any specificity of binding to a particular sequence. If chromatin is digested with this nuclease, even for longer periods, a uniform length of 146 bp DNA fragments will be formed. Explain.arrow_forward
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