Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Textbook Question
Chapter 15, Problem 11PDQ
Why are frameshift mutations likely to be more detrimental than point mutations, in which a single pyrimidine or purine has been substituted?
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Why are frameshift mutations likely to be more detrimental than point mutations, in which a single pyrimidine or purine has been substituted?
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Chapter 15 Solutions
Concepts of Genetics (12th Edition)
Ch. 15 - If a point mutation occurs within a human egg cell...Ch. 15 - One of the most famous cases of an X-linked...Ch. 15 - The cancer drug melphalan is an alkylating agent...Ch. 15 - Geneticists often use the alkylating agent...Ch. 15 - Six months pregnant, an expectant mother had a...Ch. 15 - Six months pregnant, an expectant mother had a...Ch. 15 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 15 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 15 - What is a spontaneous mutation, and why are...Ch. 15 - Prob. 4PDQ
Ch. 15 - Prob. 5PDQCh. 15 - Why is a random mutation more likely to be...Ch. 15 - Most mutations in a diploid organism are...Ch. 15 - What is the difference between a silent mutation...Ch. 15 - Describe a tautomeric shift and how it may lead to...Ch. 15 - Contrast and compare the mutagenic effects of...Ch. 15 - Why are frameshift mutations likely to be more...Ch. 15 - Why are X rays more potent mutagens than UV...Ch. 15 - DNA damage brought on by a variety of natural and...Ch. 15 - Contrast the various types of DNA repair...Ch. 15 - Mammography is an accurate screening technique for...Ch. 15 - A significant number of mutations in the HBB gene...Ch. 15 - Describe how the Ames test screens for potential...Ch. 15 - Prob. 18PDQCh. 15 - Compare DNA transposons and retrotransposons. What...Ch. 15 - Prob. 20PDQCh. 15 - In maize, a Ds or Ac transposon can alter the...Ch. 15 - Prob. 22PDQCh. 15 - In a bacterial culture in which all cells are...Ch. 15 - Presented here are hypothetical findings from...Ch. 15 - Prob. 25ESPCh. 15 - Prob. 26ESPCh. 15 - What evidence indicates that mutations in human...Ch. 15 - Among Betazoids in the world of Star Trek, the...Ch. 15 - Skin cancer carries a lifetime risk nearly equal...Ch. 15 - It has been noted that most transposons in humans...Ch. 15 - Mutations in the IL2RG gene cause approximately 30...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What is the likely consequence of a frameshift mutation?arrow_forwardWhat type of mutation is shown in the diagram? Why do you think this type of mutation is referred to by this term?arrow_forwardExplain why STR mutations are found at a much higher frequency than single nucleotide changes?arrow_forward
- What is a transposon? Explain why the insertion of a transposon into the DNA of a cell can lead to a mutationarrow_forwardWhat three different types of mutations involve changes in a single base, and what effect can each of them have on a coding sequence? Which type is the most common? Which type has the most severe effect on the function of the encoded protein?arrow_forwardWhich of the above mutations will result in a shift in the reading frame?arrow_forward
- What type of mutation (missense, silent, and non-sense) was introduced in your sequence when G was substituted with C?arrow_forward. Can a missense mutation of proline to histidine bemade with a G • C → A • T transition-causing mutagen?What about a proline-to-serine missense mutation?arrow_forwardHow does the effect of nonsense mutation differ from that of a frameshift mutation? Why?arrow_forward
- A mutant strain of bacteria is isolated in which the amino acid glutamine is often erroneously substituted for glutamic acid during protein synthesis. What kind of mutation might be underlying this defect? How could you test this hypothesis?arrow_forwardWhat is the purpose of the random hexamer primers? Why can’t a researcher use a poly-T primer in a reverse transcriptase reaction that utilizes prokaryotic mRNA as a template?arrow_forwardWhat type DNA mutation is TACAT?arrow_forward
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