Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 15, Problem 5PDQ
Summary Introduction
To determine: The reason behind considering mutations important for the process of evolution if they are thought to be deleterious.
Introduction: Mutation is defined as any change in the
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Our DNA is subject to mutations on a daily basis. Why do most mutations that occur in the genome of organisms escape detection and not elicit a deleterious effect? Why does the child of someone with cancer not necessarily develop cancer? Is it reasonable to state that mutations are essential to the evolutionary process?
Statistically, are mutations almost always beneficial or harmful? Why?
Are mutations equally likely to occur in all locations in the genome? Why or why not?
Chapter 15 Solutions
Concepts of Genetics (12th Edition)
Ch. 15 - If a point mutation occurs within a human egg cell...Ch. 15 - One of the most famous cases of an X-linked...Ch. 15 - The cancer drug melphalan is an alkylating agent...Ch. 15 - Geneticists often use the alkylating agent...Ch. 15 - Six months pregnant, an expectant mother had a...Ch. 15 - Six months pregnant, an expectant mother had a...Ch. 15 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 15 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 15 - What is a spontaneous mutation, and why are...Ch. 15 - Prob. 4PDQ
Ch. 15 - Prob. 5PDQCh. 15 - Why is a random mutation more likely to be...Ch. 15 - Most mutations in a diploid organism are...Ch. 15 - What is the difference between a silent mutation...Ch. 15 - Describe a tautomeric shift and how it may lead to...Ch. 15 - Contrast and compare the mutagenic effects of...Ch. 15 - Why are frameshift mutations likely to be more...Ch. 15 - Why are X rays more potent mutagens than UV...Ch. 15 - DNA damage brought on by a variety of natural and...Ch. 15 - Contrast the various types of DNA repair...Ch. 15 - Mammography is an accurate screening technique for...Ch. 15 - A significant number of mutations in the HBB gene...Ch. 15 - Describe how the Ames test screens for potential...Ch. 15 - Prob. 18PDQCh. 15 - Compare DNA transposons and retrotransposons. What...Ch. 15 - Prob. 20PDQCh. 15 - In maize, a Ds or Ac transposon can alter the...Ch. 15 - Prob. 22PDQCh. 15 - In a bacterial culture in which all cells are...Ch. 15 - Presented here are hypothetical findings from...Ch. 15 - Prob. 25ESPCh. 15 - Prob. 26ESPCh. 15 - What evidence indicates that mutations in human...Ch. 15 - Among Betazoids in the world of Star Trek, the...Ch. 15 - Skin cancer carries a lifetime risk nearly equal...Ch. 15 - It has been noted that most transposons in humans...Ch. 15 - Mutations in the IL2RG gene cause approximately 30...
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- If mutations occur at random with respect to an organism’s needs, how does a species become more adapted to its environment over time?arrow_forwardWhich organism violates the central dogma of molecular biology?arrow_forwardAlthough it is well known that X-rays cause mutations, they are routinely used to diagnose medical problems, including potential tumors, broken bones, and dental cavities. Why is this done? What precautions need to be taken?arrow_forward
- Two types of mutations discussed in this chapter are (1) nucleotide changes and (2) unstable genome regions that undergo dynamic changes. Describe each type of mutation.arrow_forwardIs gene transfer a form of eugenics? Is it advantageous to use gene transfer to eliminate some genetic disorders? Can this and other technology be used to influence the evolution of our species? Should there be guidelines for the use of genetic technology to control its application to human evolution? Who should create and enforce these guidelines?arrow_forwardWhy are mutations bad and at the same time good?arrow_forward
- What event contradicts the central dogma of molecular biology?arrow_forwardHow many potential evolutionary paths are there for anallele to evolve six different mutations? Seven differentmutations? Ten different mutations?arrow_forwardHighly conserved genes such as those for ribosomal RNA are present as clearly recognizable relatives in all organisms on Earth; thus, they have evolved very slowly over time. Were such genes “born” perfect?arrow_forward
- What role does epigenetics play in the process of genetic evolution?arrow_forwardIn instances in the eukaryotic genome, DNA sequences repre- sent evolutionary vestiges of duplicated copies of genes. What are such regions called and what are their characteristics?arrow_forwardSome mutations affect changes in protein structure and function that can result in disease whereas other mutations have no significant effects on protein structure and function. Please explain reasons for the above mentioned statement. Human civilization has resulted in a large number of potentially mutagenic chemicals (e.g. pesticides) and has changed the environment to increase the likelihood of encountering other mutagens, especially UV radiation. What roles should the authorities play in identifying mutagens and regulating their release into the environment?arrow_forward
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