Essential Cell Biology
Essential Cell Biology
4th Edition
ISBN: 9780815344544
Author: Keith Roberts, Karen Hopkin, Alexander D Johnson, Martin Raff, Dennis Bray, Bruce Alberts, Julian Lewis, Peter Walter
Publisher: TAYLOR
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Chapter 15, Problem 19Q
Summary Introduction

To critique:  The hypothesis “forgettin has a hydrophobic ER signal sequence at its C-terminus that is recognized by an SRP and causes it to be translocated across the ER membrane by a particular mechanism and the protein is secreted from pineal cells into bloodstream, from where it exerts its devastating systemic effects”.

Concept introduction: Human wants to forget many things, as their brain requires perfect management of memories that he or she acquired across a life time. At the same time, it has much serious impact on their life and society, and it seems to be like the brain is not working properly. Recent neuroscience studies reveal the fact that a protein called forgettin is responsible for the condition of forgetting something. This protein acts on several signalling process inside the nervous system that results in the forgetting process.

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