PRESCOTT'S MICROBIOLOGY
11th Edition
ISBN: 2818440045677
Author: WILLEY
Publisher: MCG
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Chapter 15, Problem 1AL
Summary Introduction
Telomerase is an enzyme that is responsible for the addition of telomeric units or repeats to the end of the bacterial chromosome. This enzyme is critical for maintaining the length of the telomere. Mammalian somatic cells lack the activity of this enzyme and therefore, results in the shortening of telomeres in each of the
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Inhibition of telomerase activity.
Explain: (a) What is the process affected?
(b) What is the Effect on the process?
(c) Does it affect prokaryotes, eukaryotes or both?
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Chapter 15 Solutions
PRESCOTT'S MICROBIOLOGY
Ch. 15.2 - Prob. 1CCCh. 15.2 - Prob. 2CCCh. 15.2 - Prob. 3CCCh. 15.2 - Prob. 4CCCh. 15.2 - Prob. 5CCCh. 15.3 - What functions are served by the 5 cap and the 3...Ch. 15.3 - Retrieve, Infer, Apply What elements in archaeal...Ch. 15.3 - Prob. 2CCCh. 15.3 - Prob. 3CCCh. 15.4 - Prob. 1CC
Ch. 15.4 - Prob. 2CCCh. 15.4 - Prob. 3CCCh. 15.5 - Retrieve, Infer, Apply List two similarities and...Ch. 15.5 - Prob. 2CCCh. 15.5 - Retrieve, Infer, Apply How are cis-encoded RNAs,...Ch. 15 - Prob. 1RCCh. 15 - Prob. 2RCCh. 15 - Prob. 3RCCh. 15 - Prob. 4RCCh. 15 - Prob. 5RCCh. 15 - Prob. 6RCCh. 15 - Prob. 7RCCh. 15 - Prob. 8RCCh. 15 - Prob. 9RCCh. 15 - Prob. 1ALCh. 15 - All of the subunits in bacterial RNA polymerases...Ch. 15 - Would you expect that one day microbiologists...Ch. 15 - In the chapter opening story, it was stated that...Ch. 15 - Prob. 5AL
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- Telomerase activity has been found to be 10 to 20 times more active in cancer cells than in normal somatic cells. What is the significance of this circumstance?arrow_forwardThe sequences of DNA bases below represent parts of the genes responsible for the production of one type of protein, an enzyme, produced by Botana curus and Species X, Y, and Z Under each DNA sequence, write the complementary messenger RNA base sequences that each of these gene fragments would produce. Note: Unlike during DNA replication, in the production of messenger RNA, the DNA base “A” specifies the RNA base “U.”. Use the universal genetic code table provided (see Universal Code attachment) to translate the messenger RNA base sequences into sequences of amino acids in the protein produced by each species. Write the sequences of amino acids under the messenger RNA sequences.arrow_forwardWhy do adult human cells (other than germ cells and stem cells) NOT express the enzyme telomerase? In other words what benefit does not having telomerase provide to these cells?arrow_forward
- You are a physician who has diagnosed a patient with a genetic condition that results in telomerase with lower than normal enzymatic activity. How might you have diagnosed this disease? What symptoms should be a clue? Explain.arrow_forwardScientists identify a tumor cell in rats that divides more rapidly in the presence of galactose. When they sequence the DNA of the tumor cells, they identify retroviral DNA. Explain what circumstances might have occurred that produced this phenotype.arrow_forwardYou conducted an experiment to determine the mechanism of DNA replication in the hypothetical organism Fungus mungus. Your data shows that synthesis of newly replicated DNA from F. mungus is discontinuous on both strands of the replication fork. Does this result support or not support the hypothesis that F. mungus replicates its DNA by the same mechanism as yeast? Briefly explain your answer.arrow_forward
- The genomes of most multicellular eukaryotes encode~25,000 genes, yet their proteomes contain over 200,000proteins. Propose two processes that, taken together, account for this discrepancyarrow_forwardUse the first photo to answer the following questions.arrow_forwardIf deoxyribonucleotides that lack the 3’-OH groups are added during the replication process, what do you expect will occur? Describe what happens when a nonsense mutation is introduced into the gene encoding transposase within a transposon. A pure culture of an unknown bacterium was streaked onto plates of a variety of media. You notice that the colony morphology is strikingly different on plates of minimal media with glucose compared to that seen on trypticase soy agar plates. How can you explain these differences in colony morphology?arrow_forward
- Can you please answer question 38arrow_forwardThe figure below shows the introns and exons found in gene X. The size of each exon and intron is shown as well. A study on this organism found that two mature MRNA molecules are produced for this gene. One is 457 nucleotides in length, and the other is 439 nucleotides in length. Name the process responsible for producing this variation. Also explain how these 457 and 439 nucleotide fragments were produced by referring to the information provided. Hint: This organism produces a poly-A tail of 120 nucleotides. 99 62 120 84 102 27 117 Gene X E1 в в 11 E2 12 E4 Exon (E) Intron (1)arrow_forwardThe figure below shows the introns and exons found in gene X. The size of each exon and intron is shown as well. A study on this organism found that two mature mRNA molecules are produced for this gene. One is 457 nucleotides in length, and the other is 439 nucleotides in length. Name the process responsible for producing this variation. Also explain how these 457 and 439 nucleotide fragments were produced by referring to the information provided. Hint: This organism produces a poly-A tail of 120 nucleotides.arrow_forward
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