ESSENTIALS OF GENETICS-MODIFIED ACCESS
9th Edition
ISBN: 9780134190006
Author: KLUG
Publisher: PEARSON
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Chapter 15, Problem 5PDQ
Both attenuation and riboswitches rely on changes in the secondary structure of the leader regions of mRNA to regulate gene expression. Compare and contrast the specific mechanisms in these two types of regulation.
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Explain using leucine zipper motifs as an example, how protein-protein interactions between
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Both attenuation of the trp operon in E. coli and riboswitches in B. subtilis rely on changes in the secondary structure of the leader regions of mRNA to regulate gene expression. Compare and contrast the specific mechanisms in these two types of regulation with that involving short noncoding RNAs (sRNAs).
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Chapter 15 Solutions
ESSENTIALS OF GENETICS-MODIFIED ACCESS
Ch. 15 -
CASE STUDY | A mysterious muscular dystrophy
A...Ch. 15 -
CASE STUDY |A mysterious muscular dystrophy
A...Ch. 15 -
CASE STUDY |A mysterious muscular dystrophy
A...Ch. 15 -
HOW DO WE KNOW?
1. In this chapter, we have...Ch. 15 -
2. Review the Chapter Concepts list on p. 280....Ch. 15 - Describe which enzymes are required for lactose...Ch. 15 - Contrast positive versus negative regulation of...Ch. 15 -
5. Both attenuation and riboswitches rely on...Ch. 15 - For the lac genotypes shown in the accompanying...Ch. 15 -
7. For the genotypes and conditions (lactose...
Ch. 15 -
8. The locations of numerous lacI– and lacIs...Ch. 15 - Explain why catabolite repression is used in...Ch. 15 - Describe experiments that would confirm whether or...Ch. 15 - Predict the level of genetic activity of the lac...Ch. 15 - Predict the effect on the inducibility of the lac...Ch. 15 -
13. Describe the role of attenuation in the...Ch. 15 -
14. In a theoretical operon, genes A, B, C, and D...Ch. 15 - A bacterial operon is responsible for production...Ch. 15 - A marine bacterium is isolated and is shown to...Ch. 15 -
17. Why is gene regulation more complex in a...Ch. 15 -
18. List and define the levels of eukaryotic gene...Ch. 15 -
19. Distinguish between the cis-acting regulatory...Ch. 15 - Prob. 20PDQCh. 15 - Compare the control of gene regulation in...Ch. 15 - Many eukaryotic promoter regions contain CAAT...Ch. 15 -
23. What is RNA-induced gene silencing in...Ch. 15 - Although it is customary to consider...Ch. 15 - DNA methylation is commonly associated with a...Ch. 15 - The interphase nucleus appears to be a highly...Ch. 15 - It has been estimated that at least two-thirds of...
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- During periods of starvation, translation of only vital mRNAs must occur inside a cell. Explain how eIF2 can mediate both the suppression of translation of non-essential mRNAs and ensure that essential mRNAs continues to be translated.arrow_forwardThe lac repressor and the pur repressor are homologous proteins with very similar three-dimensional structures, yet they have different effects on gene expression. Describe two important ways in which the gene-regulatory properties of these proteins differ.arrow_forwardThe post transcriptional modifications of the mature prokaryotic messenger RNA are essential in ribosome binding and stabilizing the mRA. Is this true or false?arrow_forward
- What does it mean to study the subcellular localization of a protein? What are two techniques that could be used to study the subcellular localization of a protein? Then specify how each of these techniques could be used to study a transcription factor in liver cellsarrow_forwardGenetic expression in general can be regulated at various stages. Identify specific processes that control gene expression at the: a. transcription level - b. post-transcription level - c. translation level -arrow_forwardMutation in the regulatory gene in the lac operon results in the formation of an inactive repressor. List and explain the effect of such a mutation on the expression of the structural gene for lactose in E.coli?arrow_forward
- mRNA expression level is not always a good indicator for protein expression why and what is?arrow_forwardBriefly name and explain five mechanisms by which transcription factors activate transcription, with specific reference to targets in the basal transcription complexarrow_forwardGive and briefly explain two examples of how gene expression may be repressed without altering the gene-coding sequence.arrow_forward
- Compare the control of gene regulation in eukaryotes and prokaryotes at the level of initiation of transcription. How do the regulatory mechanisms work? What are the similarities and differences in these two types of organisms in terms of the specific components of the regulatory mechanisms? Address how the differences or similarities relate to the biological context of the control of gene expression.arrow_forwardThe binding of a small effector molecule, protein-protein interactions, and covalent modifications are three common ways to modulate the activities of transcription factors. Which of these three mechanisms are used by steroid receptors and by the CREB protein?arrow_forwardmTOR must be tightly regulated because it controls both transcription and translation. true or false. explain whyarrow_forward
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