Study Guide for Campbell Biology
Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 15, Problem 7IQ
Summary Introduction

To determine: The chromosome alterations on the first chromosome of the daughter cells which produced a gene sequence of A-B-C-O-P-Q-G-J-I-H

Introduction: The errors during the process of meiosis or mutagens such as radiation can cause four types of changes in a chromosome structure. A deletion occurs due to chromosomal breakage and an entire chromosomal fragment is lost. The chromosomal fragment may attach as an extra segment to a sister chromatid or a non-sister chromatid called duplication. Inversion is the reattachment of the fragment to the original chromosome in reverse orientation. Translocation is when the chromosomal fragment becomes attached to a non-homologous chromosome.

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A phenotypically abnormal individual has a phenotypically normalfather with an inversion on one copy of chromosome 7 and a phenotypicallynormal mother without any changes in chromosomestructure. The orders of genes along the two copies of chromosome7 in the father are as follows: R T D M centromere P U X Z C (normal chromosome 7)R T D U P centromere M X Z C (inverted chromosome 7) The phenotypically abnormal offspring has a chromosome 7 withthe following order of genes: R T D M centromere P U D T R Using a sketch, explain how this chromosome was formed. In youranswer, explain where the crossover occurred (i.e., between whichtwo genes).
A wild-type chromosome has the following segments: A B C • D E F G H I Researchers have found individuals that are heterozygous for each of the following chromosome mutations. For each mutation, sketch how the wild-type and mutated chromosomes would pair in prophase I of meiosis, showing all chromosome strands. Q. A B C • D H I
An individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B • C D E F G A B • C D V W X R S • T U E F G R S • T U V W X Q. Give the products that result from alternate, adjacent-1, and adjacent-2 segregation.
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY