EBK ESSENTIALS OF GENETICS
9th Edition
ISBN: 8220102741614
Author: Palladino
Publisher: YUZU
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Chapter 16, Problem 13PDQ
Summary Introduction
To review:
(A) Difference between oncogenes and proto-oncogenes.
(B) Ways to convert proto-oncogenes to oncogenes.
Introduction:
In humans, a normal cell possesses proto-oncogene that regulates proper cell cycle and division. If these normal genes are introduced to a carcinogen then it goes under mutation, which converts the proto-oncogenes into oncogene and results in cancer.
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Chapter 16 Solutions
EBK ESSENTIALS OF GENETICS
Ch. 16 -
CASE STUDY | I thought it was safe
A middle-aged...Ch. 16 -
CASE STUDY | I thought it was safe
A middle-aged...Ch. 16 -
CASE STUDY | I thought it was safe
A middle-aged...Ch. 16 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 16 -
2. Review the Chapter Concepts list on page 307....Ch. 16 - What is the relationship between signal...Ch. 16 - Where are the major regulatory points in the cell...Ch. 16 -
5. Describe kinases and cyclins. How do they...Ch. 16 - (a) How does pRB function to keep cells at the G1...Ch. 16 - What is the difference between saying that cancer...
Ch. 16 -
8. What is apoptosis, and under what...Ch. 16 - Define tumor-suppressor genes. Why is a mutation...Ch. 16 - A genetic variant of the retinoblastoma protein,...Ch. 16 -
11. Part of the Ras protein is associated with...Ch. 16 - If a cell suffers damage to its DNA while in S...Ch. 16 - Prob. 13PDQCh. 16 - Prob. 14PDQCh. 16 - Prob. 15PDQCh. 16 - Prob. 16PDQCh. 16 - Prob. 17PDQCh. 16 - How do normal cells protect themselves from...Ch. 16 - Prob. 19PDQCh. 16 - Explain how environmental agents such as chemicals...Ch. 16 - Radiotherapy (treatment with ionizing radiation)...Ch. 16 - Genetic tests that detect mutations in the BRCA1...Ch. 16 - Prob. 23PDQCh. 16 - Prob. 24PDQCh. 16 - Prob. 25PDQCh. 16 - Prob. 26PDQCh. 16 - Prob. 27PDQCh. 16 - Prob. 28PDQ
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- What is the experimental evidence that demonstrates direct evidence that chemical carcinogens are able to produce oncogenes?arrow_forwardWhat are some examples of oncogenes?arrow_forwardWhich of the following demonstrates the link between oncogenes and cancer? The mutations in oncogenes increase the activity or number of molecules that stimulate mitosis, leading to irregular cell division. Oncogenes produce molecules that inhibit mitosis. Oncogenes do not have mutations that increase the activity or number of molecules that stimulate mitosis. Oncogenes are genes that transform tumor cells into normal cells.arrow_forward
- What are oncogenes?arrow_forwardexplain Translocations that generate oncogenesarrow_forwardWhich of the following demonstrates the link between oncogenes and cancer? a.Oncogenes do not have mutations that increase the activity or number of molecules that stimulate mitosis. b.Oncogenes produce molecules that inhibit mitosis. c.They are genes that transform tumor cells into normal cells. d.The mutations in oncogenes increase the activity or number of molecules that stimulate mitosis, leading to irregular cell division.arrow_forward
- Which of the following could be classified as an oncogene? None are possible oncogenes A mutant of MAP kinase that was active with or without being phosphorylated All are possible oncogenes A mutant of MEK with significantly reduced enzyme activity A mutant cAMP phosphodiesterase that made it super-activearrow_forwardWhat is oncogene ?arrow_forwardWhy are oncogenes usually dominant in their action, whereas tumor-suppressor genes are recessive?arrow_forward
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