It should be described that how the given structure of s o d i u m s u l f a n i l a m i d e similar to the structure of p- aminobenzoic acid . Concept introduction: In chemistry Structure is the arrangement of chemical bonds between atoms in a molecule, specifically which atoms are chemically bonded to what other atoms with what kind of chemical bond. Amines are the derivatives of ammonia ( N H 3 ) with one or more of the hydrogens replaced with a substituent such as an alkyl group. Sulfanilamide is an antibacterial which contains a sulfonamide group.

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Answer 1

Question

Chapter 16, Problem 16.47CP

(a)

Interpretation Introduction

Interpretation:

It should be described that how the given structure of sodium sulfanilamide similar to the structure of p- aminobenzoic acid.

Concept introduction:

In chemistry Structure is the arrangement of chemical bonds between atoms in a molecule, specifically which atoms are chemically bonded to what other atoms with what kind of chemical bond.

Amines are the derivatives of ammonia (NH3) with one or more of the hydrogens replaced with a substituent such as an alkyl group.

Sulfanilamide is an antibacterial which contains a sulfonamide group.

(b)

Interpretation Introduction

Interpretation:

Usually sodium salt is used as the drug rather than the neutral compound; the reason behind this should be explained.

Concept introduction:

The formation of salt involves either a proton transfer or a neutralization reaction between an acid and a base.

Drug solubility and dissolution rate greatly affect the absorption of drug.

The salt form of a drug is usually more soluble than the parent drug.

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Answer 2

Question

Chapter 16, Problem 16.47CP

(a)

Interpretation Introduction

Interpretation:

It should be described that how the given structure of sodium sulfanilamide similar to the structure of p- aminobenzoic acid.

Concept introduction:

In chemistry Structure is the arrangement of chemical bonds between atoms in a molecule, specifically which atoms are chemically bonded to what other atoms with what kind of chemical bond.

Amines are the derivatives of ammonia (NH3) with one or more of the hydrogens replaced with a substituent such as an alkyl group.

Sulfanilamide is an antibacterial which contains a sulfonamide group.

(b)

Interpretation Introduction

Interpretation:

Usually sodium salt is used as the drug rather than the neutral compound; the reason behind this should be explained.

Concept introduction:

The formation of salt involves either a proton transfer or a neutralization reaction between an acid and a base.

Drug solubility and dissolution rate greatly affect the absorption of drug.

The salt form of a drug is usually more soluble than the parent drug.

Expert Solution & Answer

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See solution

Answer 3

Question

Chapter 16, Problem 16.47CP

(a)

Interpretation Introduction

Interpretation:

It should be described that how the given structure of sodium sulfanilamide similar to the structure of p- aminobenzoic acid.

Concept introduction:

In chemistry Structure is the arrangement of chemical bonds between atoms in a molecule, specifically which atoms are chemically bonded to what other atoms with what kind of chemical bond.

Amines are the derivatives of ammonia (NH3) with one or more of the hydrogens replaced with a substituent such as an alkyl group.

Sulfanilamide is an antibacterial which contains a sulfonamide group.

(b)

Interpretation Introduction

Interpretation:

Usually sodium salt is used as the drug rather than the neutral compound; the reason behind this should be explained.

Concept introduction:

The formation of salt involves either a proton transfer or a neutralization reaction between an acid and a base.

Drug solubility and dissolution rate greatly affect the absorption of drug.

The salt form of a drug is usually more soluble than the parent drug.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 16, Problem 16.47CP

(a)

Interpretation Introduction

Interpretation:

It should be described that how the given structure of sodium sulfanilamide similar to the structure of p- aminobenzoic acid.

Concept introduction:

In chemistry Structure is the arrangement of chemical bonds between atoms in a molecule, specifically which atoms are chemically bonded to what other atoms with what kind of chemical bond.

Amines are the derivatives of ammonia (NH3) with one or more of the hydrogens replaced with a substituent such as an alkyl group.

Sulfanilamide is an antibacterial which contains a sulfonamide group.

(b)

Interpretation Introduction

Interpretation:

Usually sodium salt is used as the drug rather than the neutral compound; the reason behind this should be explained.

Concept introduction:

The formation of salt involves either a proton transfer or a neutralization reaction between an acid and a base.

Drug solubility and dissolution rate greatly affect the absorption of drug.

The salt form of a drug is usually more soluble than the parent drug.

Expert Solution & Answer

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See solution

Answer 5

Chapter 16, Problem 16.47CP

(a)

Interpretation Introduction

Interpretation:

It should be described that how the given structure of sodium sulfanilamide similar to the structure of p- aminobenzoic acid.

Concept introduction:

In chemistry Structure is the arrangement of chemical bonds between atoms in a molecule, specifically which atoms are chemically bonded to what other atoms with what kind of chemical bond.

Amines are the derivatives of ammonia (NH3) with one or more of the hydrogens replaced with a substituent such as an alkyl group.

Sulfanilamide is an antibacterial which contains a sulfonamide group.

(b)

Interpretation Introduction

Interpretation:

Usually sodium salt is used as the drug rather than the neutral compound; the reason behind this should be explained.

Concept introduction:

The formation of salt involves either a proton transfer or a neutralization reaction between an acid and a base.

Drug solubility and dissolution rate greatly affect the absorption of drug.

The salt form of a drug is usually more soluble than the parent drug.

Answer 6

Chapter 16, Problem 16.47CP

(a)

Interpretation Introduction

Interpretation:

It should be described that how the given structure of sodium sulfanilamide similar to the structure of p- aminobenzoic acid.

Concept introduction:

In chemistry Structure is the arrangement of chemical bonds between atoms in a molecule, specifically which atoms are chemically bonded to what other atoms with what kind of chemical bond.

Amines are the derivatives of ammonia (NH3) with one or more of the hydrogens replaced with a substituent such as an alkyl group.

Sulfanilamide is an antibacterial which contains a sulfonamide group.

Answer 7

Chapter 16, Problem 16.47CP

(a)

Interpretation Introduction

Interpretation:

It should be described that how the given structure of sodium sulfanilamide similar to the structure of p- aminobenzoic acid.

Concept introduction:

In chemistry Structure is the arrangement of chemical bonds between atoms in a molecule, specifically which atoms are chemically bonded to what other atoms with what kind of chemical bond.

Amines are the derivatives of ammonia (NH3) with one or more of the hydrogens replaced with a substituent such as an alkyl group.

Sulfanilamide is an antibacterial which contains a sulfonamide group.

Answer 8

(b)

Interpretation Introduction

Interpretation:

Usually sodium salt is used as the drug rather than the neutral compound; the reason behind this should be explained.

Concept introduction:

The formation of salt involves either a proton transfer or a neutralization reaction between an acid and a base.

Drug solubility and dissolution rate greatly affect the absorption of drug.

The salt form of a drug is usually more soluble than the parent drug.

Answer 9

(b)

Interpretation Introduction

Interpretation:

Usually sodium salt is used as the drug rather than the neutral compound; the reason behind this should be explained.

Concept introduction:

The formation of salt involves either a proton transfer or a neutralization reaction between an acid and a base.

Drug solubility and dissolution rate greatly affect the absorption of drug.

The salt form of a drug is usually more soluble than the parent drug.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 16.2 - Identify the following compounds as primary,...Ch. 16.2 - Prob. 16.2P Ch. 16.2 - Prob. 16.3P Ch. 16.2 - Prob. 16.4P Ch. 16.2 - Prob. 16.5KCP Ch. 16.2 - Prob. 16.6KCP Ch. 16.3 - Arrange the following compounds in order of...Ch. 16.3 - Draw the structures of (a) ethylamine and (b)...Ch. 16.4 - Provide compounds that fit the following...Ch. 16.4 - Prob. 16.10P

Solution Summary: The author explains that sodium sulfanilamide is structurally analogues to PABA and is used as the drug rather than the neutral compound.

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Chapter 16 Solutions