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EBK CONCEPTS OF GENETICS
12th Edition
ISBN: 9780134818979
Author: Killian
Publisher: YUZU
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Chapter 16, Problem 23ESP
Summary Introduction
To propose: An experiment for differentiating two types of mutations.
Introduction: The variations caused in the genetic material of an organism from a source or randomly are called mutations. The minute changes in the DNA fragment caused the new variations among the individuals, which makes them different from each other.
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Students have asked these similar questions
The table below shows different types of mutations in different positions in four genes. Choose the letter (A to E), from the
drop-down menu, that represents the most likely type of protein that will be produced from each of these mutated genes.
A: completely normal protein
B: functional protein with ONE amino acid different from normal
C: non-functional protein with ONE amino acid different from normal
D: non-functional protein with MANY amino acids different from normal
E: no protein at all
Answer
Type of mutation
Position of mutation in gene
(A, B, C, D, or E)
before the part of the gene that specifies
the active site of the enzyme
2 base pair insertion
Inonsense
immediately before the stop codon
in the part of the gene that specifies the
active site of the enzyme
silent
1 base pair insertion
in an intron
You are working in the lab with two known carcinogens found in cigarette smoke: Benzo(a)pyren (BaP) and nitrosamine ketone (NNK). BaP is an aromatic hydrocarbon and the mechanism of carcinogenesis is through oxidation reactions with DNA. NNK is a nitrosoamine. Describe how these two kinds of carcinogens lead to mutations. (Be detailed. Remember you are graded on effort/completeness.)
A chemist synthesizes four new chemical compounds in the laboratory and names them PFI1, PFI2, PFI3, and PFI4. He gives the PFI compounds to a geneticist friend and asks her to determine their mutagenic potential. The geneticist finds that all four are highly mutagenic. She also tests the capacity of mutations produced by the PFI compounds to be reversed by other known mutagens and obtains the following results. What conclusions can you make about the nature of the mutations produced by these compounds? Reversed by Mutations produced by 2- Aminopurine Nitrous acid Hydroxylamine Acridine orange PFI1 Yes Yes Some No PFI2 No No No No PFI3 Yes Yes No No PFI4 No No No Yes
Chapter 16 Solutions
EBK CONCEPTS OF GENETICS
Ch. 16 - Even though the lac Z, Y, and A structural genes...Ch. 16 - Predict the level of genetic activity of the lac...Ch. 16 - Prob. 1CSCh. 16 - Prob. 2CSCh. 16 - Prob. 3CSCh. 16 - HOW DO WE KNOW? In this chapter, we focused on the...Ch. 16 - Prob. 2PDQCh. 16 - Contrast positive versus negative control of gene...Ch. 16 - Contrast the role of the repressor in an inducible...Ch. 16 - For the lac genotypes shown in the following...
Ch. 16 - For the genotypes and conditions (lactose present...Ch. 16 - The locations of numerous lacI and lacIS mutations...Ch. 16 - Prob. 8PDQCh. 16 - Prob. 9PDQCh. 16 - Predict the effect on the inducibility of the lac...Ch. 16 - Erythritol, a natural sugar abundant in fruits and...Ch. 16 - Prob. 12PDQCh. 16 - Prob. 13PDQCh. 16 - Neelaredoxin is a 15-kDa protein that is a gene...Ch. 16 - The creation of milk products such as cheeses and...Ch. 16 - Both attenuation of the trp operon in E. coli and...Ch. 16 - Prob. 17PDQCh. 16 - Prob. 18ESPCh. 16 - In a theoretical operon, genes A, B, C, and D...Ch. 16 - A bacterial operon is responsible for the...Ch. 16 - A marine bacterium is isolated and shown to...Ch. 16 - Prob. 22ESPCh. 16 - Prob. 23ESP
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- A chemist synthesizes four new chemical compounds in the laboratory and names them PFI1, PFI2, PFI3, and PFI4. He gives the PFI compounds to a geneticist friend and asks her to determine their mutagenic potential. The geneticist finds that all four are highly mutagenic. She also tests the capacity of mutations produced by the PFI compounds to be reversed by other known mutagens and obtains the following results. What conclusions can you make about the nature of the mutations produced by these compounds? Reversed by Mutations, Nitrous, Aminopurine acid Acridine orange 2- produced by Hydroxylamine PFI1 Yes Yes Some No PFI2 No No No No PFI3 Yes Yes No No PFI4 No No No Yesarrow_forwardSuppose that you could undergo genetic testing at age 18 for susceptibility to a genetic disease that would not appear until middle age and has no available treatment. a. What would be some of the possible reasons for having such a genetic test and some of the possible reasons for not having the test? b. Would you personally want to be tested? Explain your reasoning.arrow_forwardGive a schematic diagram of how we can Treatment Down's syndrome by using gene therapy? Please answer at your own words,please..arrow_forward
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- Huntington disease (HD) can arise from a rare, short, in-frame addition of CAG nucleotide triplets within the huntingtin (HTT) gene coding region, which creates a disease-causing allele with the symptoms only appearing later in life. Using this information, describe an experiment that could be undertaken to determine whether a currently healthy young individual is a carrier of the HD-causing mutation. Describe the method you would use and how you would interpret the results of this experiment.arrow_forwardUnanswered As a hobby you propagate a population of worms. You notice that one worm is now clear instead of being tan. You trace down the mutation and discover that it is a single basepair deletion in a pigmentation gene. Explain how a single basepair deletion could result in a drastic mutant phenotype. Your answer Write your response here... ion onarrow_forwardPerfect Day Foods is one company creating a synthetic milk alternative. It's similar to milk in that it consists of casein and whey, the proteins found in milk. However, a cow was never used to produce their product. Instead, the animal-free dairy product is made in a lab using yeast programmed with DNA to produce the same proteins found in cow’s milk. a. Describe the technology that was used to generate yeast programmed to produce milk proteins.arrow_forward
- Which of the following terms refer to the case when a mutation results in a significant decrease or a complete loss of the functional activity of a gene product? a. gain-of-function mutation b. loss-of-function mutationarrow_forwardThe genetic alteration responsible for sickle-cell anemia in humans involves: a transition mutation from A to G, substituting glutamic acid for valine in a-globin a transversion mutation from T to A, substituting valine for glutamic acid in b-globin a transition mutation from T to C, substituting valine for glutamic acid in b-globin a transversion mutation from G to C, substituting glutamic acid for valine in a-globin a frameshift mutation of one ATC codon, removing glutamic acid from b-globinarrow_forwardIdentify the following sources of induced mutations, all of which increase the rate of mutation in human body cells. Choose between physical mutagens and chemical mutagens for each). Radiation exposures from airport security and during high altitude air travel. Answer Ingredients such as toluene and dibutyl phthalate in nail polish. Answer Exposure to BPA by heating up food wrapped in plastic wraps in microwaves. Answer Obtaining a base tan at a tanning salon prior to a beach vacation. Answerarrow_forward
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