Biochemistry (Looseleaf)
9th Edition
ISBN: 9781319114800
Author: BERG
Publisher: MAC HIGHER
expand_more
expand_more
format_list_bulleted
Question
Chapter 16, Problem 3P
Interpretation Introduction
Interpretation: The true statement needs to be identified and explained.
Concept Introduction :
In the absence of oxygen, muscle cells produce energy by converting glucose into lactate. The process of conversion of glucose into lactic acid is termed as lactic acid fermentation. It is catalyzed by the enzyme lactate dehydrogenase (LDH). In various animals, lactate produced in the muscles is recycled back to glucose in the liver.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Long explanations are NOT NEEDED.
ATP accounting.
Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation.
a. Number of pyruvate molecules after glycolysis.b. Net ATP produced in glycolysis only (via substrate-level phosphorylation).c. Number of NADH produced using the pyruvate dehydrogenase complex reaction.d. Number of NADH and FADH2 produced from Krebs cycle.e. Net ATP produced (complete oxidation via Malate aspartate shuttle).
Butch Cassidy and the Sundance Kid. Glutamate dehydrogenase
requires which of the following cofactors:
a. NAD+/NADP+NAD*/NADP+
b. Pyridoxal phosphate
c. Thiamine pyrophosphate
d. Biopterin
The Cori Cycle. Before vigorous exercise (at rest) the level of blood lactate is at its normal level (about 25 mM). During a 400 m sprint, the value rises sharply in less than a few minutes to about 200 mM and then declines slowly to around 40 mM over 60 mins after the sprint.
a. Discuss (or illustrate) the pathway and reactions that cause the rapid increase in lactate concentration during the sprint.
b. What causes the slow decline in lactate concentration after the sprint? Why does the decrease occur more slowly than the rapid increase?
c. What enzymatic reaction is responsible for maintaining the lactate concentration above zero at recovery after the sprint?
Chapter 16 Solutions
Biochemistry (Looseleaf)
Ch. 16 - Prob. 1PCh. 16 - Prob. 2PCh. 16 - Prob. 3PCh. 16 - Prob. 4PCh. 16 - Prob. 5PCh. 16 - Prob. 6PCh. 16 - Prob. 7PCh. 16 - Prob. 8PCh. 16 - Prob. 9PCh. 16 - Prob. 10P
Ch. 16 - Prob. 11PCh. 16 - Prob. 12PCh. 16 - Prob. 13PCh. 16 - Prob. 14PCh. 16 - Prob. 15PCh. 16 - Prob. 16PCh. 16 - Prob. 17PCh. 16 - Prob. 18PCh. 16 - Prob. 19PCh. 16 - Prob. 20PCh. 16 - Prob. 21PCh. 16 - Prob. 22PCh. 16 - Prob. 23PCh. 16 - Prob. 24PCh. 16 - Prob. 25PCh. 16 - Prob. 26PCh. 16 - Prob. 27PCh. 16 - Prob. 28PCh. 16 - Prob. 29PCh. 16 - Prob. 30PCh. 16 - Prob. 31PCh. 16 - Prob. 32PCh. 16 - Prob. 33PCh. 16 - Prob. 34PCh. 16 - Prob. 35PCh. 16 - Prob. 36PCh. 16 - Prob. 37PCh. 16 - Prob. 38PCh. 16 - Prob. 39PCh. 16 - Prob. 40PCh. 16 - Prob. 41PCh. 16 - Prob. 42PCh. 16 - Prob. 43PCh. 16 - Prob. 44PCh. 16 - Prob. 45PCh. 16 - Prob. 46PCh. 16 - Prob. 47PCh. 16 - Prob. 48PCh. 16 - Prob. 49PCh. 16 - Prob. 50PCh. 16 - Prob. 51PCh. 16 - Prob. 52PCh. 16 - Prob. 53PCh. 16 - Prob. 54PCh. 16 - Prob. 55PCh. 16 - Prob. 56PCh. 16 - Prob. 57PCh. 16 - Prob. 58PCh. 16 - Prob. 59PCh. 16 - Prob. 60PCh. 16 - Prob. 61P
Knowledge Booster
Similar questions
- . Avidin is a protein that binds extremely tightly to biotin. Therefore, it is a potent inhibitor of biotin-requiring enzyme reac- tions. Consider glucose biosynthesis from each of the following substrates and predict which of these pathways would be inhibited by avidin. (a) Lactate (b) Oxaloacetate (c) Malate (d) Fructose-6-phosphate (e) Phosphoenolpyruvatearrow_forwardFill in the blanks. Acetaminophen toxicity can occur at high doses in the liver. because ___________ (what type of molecules?) can become saturated and other routes of metabolism take over.Please explain to me what the correct molecule(?) is and why it is correct. I understand that the glucuronidation and sulfation conjugation pathways become saturated, but am not understanding what molecule(s) it is/are that is/are becoming saturated leading to the other routes of metabolism and acetaminophen toxicity.arrow_forward. Pyruvate can be processed under anaerobic conditions to ethanol (in yeast) or to lactate (in mammals), as shown. Explain the primary purpose of these reactions. Describe the major biochemical features of each reactionarrow_forward
- Long explanations are not needed. Direct answers would suffice. a. Anaerobic glycolysis can produce ATP at a much faster rate than aerobic oxidative phosphorylation. I. True II. False b. Phosphorylases and phosphatases catalyze the same reaction, the removal of a phosphate group. I. True II. Falsearrow_forwardCompare and contrast regulation of gluconeogenesis and glycolysis rates. Part I. Complete the table by replacing question mark (?) with "high" or "low" as required. [lactate] (high/low) high high high high low low (glucose) (highlow) high | high ATPMAMP] (high/low) | high low high low high low high low Rate glycolysis (highſow) Rate GNG (high/low) ? low low high | high low low low low Part II. (Each row in the table is a separate condition. Interpret each condition independently) Annotation: Prepare to explain the rates. Extra Credit. Blood glucose ranges 5.5 mM and 7.1 mM. The Km for hexokinase is 10 mM in liver and 0.1 mM in muscle. Explain how each condition may or may not arise in muscle, liver, or both.arrow_forwardLong explanations are NOT NEEDED. ATP accounting. Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation. d. Number of NADH and FADH2 produced from Krebs cycle.e. Net ATP produced (complete oxidation via Malate aspartate shuttle).arrow_forward
- Required partner. Aminotransferases require which of the following cofactors: a. NAD+/NADP+NAD+/NADP+ b. Pyridoxal phosphate c. Thiamine pyrophosphate d. Biopterinarrow_forwardHelp me understand this…I’m confusedarrow_forwardThe Big Picture " - Metabolic Integration. Metabolic pathways are regulated to maintain homeostasis in the face of changing environmental conditions, such as food supply. Explain how this is achieved during the fed-fast cycle using pathways important for three macronutrients (CHOs, lipids, protein). Also, specify the Signal(s) involved in the modulation of these paths.arrow_forward
- Long explanations are NOT NEEDED. Answer only d and e. ATP accounting. Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation. -Number of pyruvate molecules after glycolysis is 4.-Net ATP produced in glycolysis only (via substrate-level phosphorylation) is 2.-Number of NADH produced using the pyruvate dehydrogenase complex reaction is 1. Now find:d. Number of NADH and FADH2 produced from Krebs cycle.e. Net ATP produced (complete oxidation via Malate aspartate shuttle).arrow_forwardLong explanations are not needed. Direct answers would suffice. a. In the TCA cycle, succinate dehydrogenase channels electrons directly into the electron transfer chain. I. True II. False b. Glucagon is a hormone that activates glycogenolysis. I. True II. Falsearrow_forward. Describe the reaction steps of the citric acid cycle with a focus on their control. In addition discuss the energy provided to a living cell from the metabolism of one acetyl-CoA entering the citric acid cyclearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. FreemanLehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. FreemanFundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage LearningBiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningFundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON