Microbiology: An Evolving Science (Fourth Edition)
Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393614039
Author: SLONCZEWSKI, Joan L., Foster, John W.
Publisher: W. W. Norton & Company
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Chapter 16.6, Problem 1TQ
Summary Introduction

To review:

The usage of different industrial strains or species to express different forms of cloned products.

Introduction:

The characteristics and growth cycle of an industrial strain are known. The strain can be optimized according to the requirement. The industrial strain should possess some key properties such as genetic stability, easily manipulated, non-toxic, inexpensive, efficient gene expression, and the product should be ready for harvestation.

Expert Solution & Answer
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Explanation of Solution

Different types of industrial strains possess distinct kinds of biochemical systems that favor various products. For instance, certain types of fungi naturally contain the complex mechanisms for the production of antibiotics. They also possess mechanisms to regulate the timing of switching on these pathways after the cell population has achieved a sufficient population density.

Bacterial cells such as Bacillus subtilis are highly predictable when it comes to their growth cycles. They do not pose much difficulty when manipulated in order to express the recombinant products such as human genes encoding several essential proteins. The bacterial cells multiply at a much faster rate and hence, the production of desired products can be achieved at maximum.

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