Biology: Concepts and Investment (Comprehensive Instructor's)
Biology: Concepts and Investment (Comprehensive Instructor's)
4th Edition
ISBN: 9781259869655
Author: Hoefnagels
Publisher: MCG
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Chapter 17, Problem 4WIO

If you were developing a new "broad-spectrum" antibiotic to kill a wide variety of bacteria, which cell structures and pathways would you target? Which of those targets also occur in eukaryotic cells, and why is that important? How would your strategy change if you were designing a new "narrow-spectrum" antibiotic active against only a few types of bacteria?

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Which of the following best describes the mechanism of action of the antibiotic streptomycin? A. it disrupts protein synthesis in resistant bacteria. B. Streptomycin inhibits cell wall synthesis in all bacterial species. C. Streptomycin creates mutations in bacteria which cause them to become resistant. D. It disrupts protein synthesis in nonresistant bacteria.
Engineered bacteria are commonly used and cultured in pharmaceutical laboratories to produced drugs like insulin. However, during one instance, with the desire to increase the rate of insulin production, one scientist tried to modify the process and put another substance (chemical x) in the growth medium which is chemically almost the same to the substance (chemical x’) normally put in the medium. After which, the scientist found out that the amount of insulin produced in the medium decreases as compared to the normal production. Again, within the context of our discussion, explain the possible reason for the observed result.
Why do bacteria that are not genetically resistant to antibiotics die out when exposed to antibiotics?

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Biology: Concepts and Investment (Comprehensive Instructor's)

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Bacterial Genomics and Metagenomics; Author: Quadram Institute;https://www.youtube.com/watch?v=_6IdVTAFXoU;License: Standard youtube license