(a)
Interpretation: The Given compounds can be prepared using a Reformatsky reaction has to be described.
Concept introduction: An
On acidic hydrolysis of ester, the
(b)
Interpretation: The Given compounds can be prepared using a Reformatsky reaction has to be described.
Concept introduction: An aldehyde or ketone is reacted with an organozinc reagent. The organozinc reagent is added to the carbonyl of aldehyde. The final product on hydrolysis is required
On acidic hydrolysis of ester, the carboxylic acid can be obtained. To remove a molecule of water, the
(c)
Interpretation: The Given compounds can be prepared using a Reformatsky reaction has to be described.
Concept introduction: An aldehyde or ketone is reacted with an organozinc reagent. The organozinc reagent is added to the carbonyl of aldehyde. The final product on hydrolysis is required
On acidic hydrolysis of ester, the carboxylic acid can be obtained. To remove a molecule of water, the
(d)
Interpretation: The Given compounds can be prepared using a Reformatsky reaction has to be described.
Concept introduction: An aldehyde or ketone is reacted with an organozinc reagent. The organozinc reagent is added to the carbonyl of aldehyde. The final product on hydrolysis is required
On acidic hydrolysis of ester, the carboxylic acid can be obtained. To remove a molecule of water, the
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Pearson eText Organic Chemistry -- Instant Access (Pearson+)
- The Reformatsky reaction is an addition reaction in which an organozinc reagent is used instead of a Grignard reagent to add to the carbonyl group ofan aldehyde or a ketone. Because the organozinc reagent is less reactive than a Grignard reagent, a nucleophilic addition to the ester group does not occur.The organozinc reagent is prepared by treating an a-bromo ester with zinc. Describe how each of the following compounds can be prepared, using a Reformatsky reaction:arrow_forwardIdentify the best reagents to complete the following reaction.arrow_forwardPropose a mechanism for the reaction of benzyl acetate with methylamine. Label theattacking nucleophile and the leaving group, and draw the transition state in which theleaving group leaves.arrow_forward
- Starting with cyclohexanone and ethanol as the only organic reagents, use any inorganic reagents to propose a synthesis for the target molecule.arrow_forwardWrite the reagents used to synthesise the following compound starting from the benzoic acidarrow_forwardThe following substances can be prepared by a nucleophilic addition reaction between an aldehyde or ketoneand a nucleophile. Identify the reactants from which they were prepared. If the substance is an acetal, identifythe carbonyl compound and the alcohol; if it is an imine or enamine, identify the carbonyl compound and theamine. You do not have to consider stereochemistry. In cases where there is more than one answer, just giveone. Use Grignard reagents when an organometallic reagent is required. Draw the Grignard reagent as acovalent magnesium bromide.arrow_forward
- Following ester (methyl benzoate) was hydrolyzed in presence of an acid catalyst. This reaction produces --- and ---. OCH3 benzoic acid, ethanol benzoic acid, water acetic acid, benzene benzoic acid, methanolarrow_forwardIdentify the best reagents to complete the following reaction. HO, CIarrow_forwardWhich of the following is not the result of a nucleophilic addition to a ketone or aldehyde?arrow_forward
- Draw out the reaction mechanism for cyclohexanol to cyclohexanone. Sodium hypochlorite oxidation of an alcohol to a ketone with the product being cyclohexanone.arrow_forwardDraw the products obtained by reacting a sulfonitric mixture with: 4-nitrophenol, 2,4-dinitrophenol, phenol, 4-methoxyphenol, 4-chlorophenol.arrow_forwardWhat is the product of a Grignard reaction? O A 2° or 3° amine with the nitrogen bound to the R group from the Grignard reagent. O A six-membered ring. O An ester that incorporates the R group from the Grignard reagent. O A 2° or 3° alcohol with the a carbon bound to the R group from the Grignard reagent. Question 5 How do you prepare a Grignard reagent? O React an organohalide with magnesium metal. O React a carbonyl-containing compound with an organohalide. O Mix an organohalide with mollen magneshum. O React a carbonyl containing compound with magnesiummetal.arrow_forward
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