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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 18, Problem 16QP
Textbook Problem
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A region on chromosome 6 has been linked to schizophrenia, but researchers have not found a specific gene associated with this disease. What steps would be necessary to locate the gene?

Summary Introduction

To determine: The necessary steps to locate the gene when a region on chromosome 6 has been linked to schizophrenia, but researchers have not found a specific gene associated with this disease.

Introduction: Schizophrenia is characterized by thought disorders, delusions, and anti social behavior. This is much common in children and at least lasts for 6 months. The genes associated with schizophrenia are found within a region of DNA located on chromosome 6.

Explanation of Solution

To locate a gene on chromosome 6 linked to schizophrenia, investigator would need to perform single nucleotide polymorphism (SNP) marker in that region.

The steps involved to locate the gene when a region on chromosome 6 has been linked to schizophrenia are as follows:

  • • Sample from monozygotic twins is preferable when one is affected from schizophrenia.
  • • Investigator should round up the sample of individuals which are affected from schizophrenia...

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