Concept explainers
Interpretation:
Effect of hemoglobin when substitution of valine for glutamic acid in primary structure of hemoglobin has to be identified.
Concept introduction:
Many amino acids are linked together through amide bonds to form a biologically large molecule known to be proteins.
Amino functional group is
Primary structure of protein is a sequence in which the amino acids linked by peptide bond in a protein.
Sickle-cell anemia is a hereditary disease caused by genetic difference that replaces one amino acid (glutamate) with another in each of the two polypeptide chains of the hemoglobin.
Want to see the full answer?
Check out a sample textbook solutionChapter 18 Solutions
Modified Mastering Chemistry With Pearson Etext -- Standalone Access Card -- For Fundamentals Of General, Organic, And Biological Chemistry (8th Edition)
- BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. FreemanLehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. FreemanFundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage LearningBiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningFundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON