BROOKER BIOLOGY
BROOKER BIOLOGY
5th Edition
ISBN: 9781307656152
Author: BROOKER
Publisher: MCG/CREATE
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Chapter 18, Problem 1COQ
Summary Introduction

To determine: The environmental agents that induce epigenetic changes leading to cancer.

Introduction: Epigenetics deals with the changes in gene expression and chromatin without changing the DNA structure. DNA methylation at cytosines, histone modification (acetylation) and RNA interference are three major epigenetic changes that are inheritable. Notably, the epigenetic status is altered in cancer cells.

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Go to the PubMed website and search the words epigenetic and cancer.Scan through the journal articles you retrieve and make a list of environmental agents that may cause epigenetic changes that contributeto cancer.
Define Epigenetic changes.  Are epigenetic changes the same thing as mutations?  Explain why or why not.
Let’s suppose you were interested in developing drugs to preventepigenetic changes that may contribute to cancer. What cellularproteins would be the target of your drugs? What possible sideeffects might your drugs cause?
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