The given following esters which cannot undergo claisen condensation has to be predicted. Concept introduction: When two molecules of an ester undergo condensation is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile. A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base. The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.

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Answer 1

Question

Chapter 18.13, Problem 28P

Interpretation Introduction

Interpretation: The given following esters which cannot undergo claisen condensation has to be predicted.

Concept introduction: When two molecules of an ester undergo condensation is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile.

A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base.

The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.

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Answer 2

Question

Chapter 18.13, Problem 28P

Interpretation Introduction

Interpretation: The given following esters which cannot undergo claisen condensation has to be predicted.

Concept introduction: When two molecules of an ester undergo condensation is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile.

A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base.

The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.

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Answer 3

Question

Chapter 18.13, Problem 28P

Interpretation Introduction

Interpretation: The given following esters which cannot undergo claisen condensation has to be predicted.

Concept introduction: When two molecules of an ester undergo condensation is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile.

A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base.

The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.

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Answer 4

Question

Chapter 18.13, Problem 28P

Interpretation Introduction

Interpretation: The given following esters which cannot undergo claisen condensation has to be predicted.

Concept introduction: When two molecules of an ester undergo condensation is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile.

A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base.

The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.

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Answer 5

Chapter 18.13, Problem 28P

Interpretation Introduction

Interpretation: The given following esters which cannot undergo claisen condensation has to be predicted.

Concept introduction: When two molecules of an ester undergo condensation is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile.

A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base.

The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.

Answer 6

Chapter 18.13, Problem 28P

Interpretation Introduction

Interpretation: The given following esters which cannot undergo claisen condensation has to be predicted.

Concept introduction: When two molecules of an ester undergo condensation is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile.

A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base.

The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.

Answer 7

Chapter 18.13, Problem 28P

Interpretation Introduction

Interpretation: The given following esters which cannot undergo claisen condensation has to be predicted.

Concept introduction: When two molecules of an ester undergo condensation is called claisen condensation. Like in aldol reaction, in claisen condensation one molecule is a nucleophile and the other molecule is an electrophile.

A claisen condensation reaction is a reversible reaction and occurs in the presence of a strong base.

The first step of claisen condensation is the removal of a proton from alpha carbon by a base and then the addition of enolate ion formed to the second ester molecule forming a β-ketoester.

Answer 8

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Answer 9

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Answer 11

Ch. 18.1 - Prob. 1P Ch. 18.1 - Prob. 2P Ch. 18.1 - Prob. 3P Ch. 18.1 - Prob. 4P Ch. 18.1 - PROBLEM 5♦ List the compounds in each of the...Ch. 18.2 - Explain why 92% of 2,4-pemtanedione exists as the...Ch. 18.3 - Draw the enol tautomers for each of the following...Ch. 18.3 - Prob. 8P Ch. 18.4 - Prob. 9P Ch. 18.4 - Prob. 10P

Solution Summary: The author explains that claisen condensation occurs when two molecules of an ester undergo condensation, like in aldol reaction.

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