Concept explainers
(a)
Interpretation:
The complete equation for the hydrolysis of the given amide in concentrated aqueous
Concept introduction:
Amide hydrolysis in aqueous base:
A carboxylate salt and ammonia or an
For each mole of amide, one mole of base is required.
(b)
Interpretation:
The complete equation for the hydrolysis of the given amide in concentrated aqueous
Concept introduction:
Amide hydrolysis in aqueous base:
A carboxylate salt and ammonia or an amine will be the product of amide hydrolysis in aqueous base.
For each mole of amide, one mole of base is required.
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Chapter 18 Solutions
OWL V2 with MindTap Reader and Student Solutions Manual eBook for Brown/Iverson/Anslyn/Foote's Organic Chemistry, 8th Edition
- Compounds like amphetamine that contain nitrogen atoms are protonated by the HCl in the gastric juices of the stomach, and the resulting salt is then deprotonated in the basic environment of the intestines to regenerate the neutral form. Write proton transfer reactions for both of these processes.arrow_forwardComplete equations for the hydrolysis of the amides in concentrated aqueous NaOH. Show all products as they exist in aqueous NaOH and the number of moles of NaOH required for hydrolysis of each amide.arrow_forward8 (Chemical Connections 19C) Once it has been opened, and particularly if it has been left open to the air, a bottle of aspirin may develop a vinegar-like odor. Explain how this might happen.arrow_forward
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- Draw the structures of the products when each of the following amides undergo hydrolysis with NaOH. You may want to reference (Page) Section 18.6 while completing this problem. ▼ CH3 0 CH,—CH,—CH—C—NH, Draw the molecules on the canvas by choosing buttons from the Tools (for bonds and charg www NN [1] Submit Part B Request Answer H 120 EXP CONT + Marvin JS by ChemAxon • & H H 120 EXP CONT C N O S CI Br - PFL O CH₂ CH3 CH3-CH₂-CH₂-C-N-CH₂-CH3 Draw the molecules on the canvas by choosing buttons from the Tools (for bonds and charg Р H C Z Oarrow_forwardWrite the products of the reaction of diphenhydramine (a base) with the acid HCl shown below. Are the reactants or products more soluble in water? Briefly explain.arrow_forwardBisphenol A is widely used as a building block in polymer synthesis and is found in the polycarbonate hard plastics of reusable drink containers, DVDs, cell phones, and other consumer goods. Bisphenol A is reported to have estrogenic activity, and its widespread occurrence in our environment is a potential concern. Describe one or two biochemical experiments that could be done to compare the activity of bisphenol A with that of its estradiol, its structural relative.arrow_forward
- Name (by the common system of nomenclature) the amine (or ammonia) that is formed by the basic hydrolysis of the following acid amide: 01C NH₂arrow_forwardExplain why CH3 CH2 CH2NH2 is a Brønsted base. Its water solutions are basic. All substances containing nitrogen atoms are Brønsted bases. This amine is a proton donor. This amine can ассеpt a proton from a proton donor.arrow_forward11. Write the chemical reaction for the acid hydrolysis of each amide sample. Include the 유 condensed structural formulas of the reactants and products. 11 CH3-C-NH₂ +H20+HCI CH3-C-OH + NH4+ CI- ACETAMIDE SO -NH2 +H20 T → 0 COOH + NH 3 11arrow_forward
- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage LearningOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning