Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 19, Problem 12QP
Summary Introduction
To determine: The allele frequencies when a trait is determined by autosomal recessive allele and occurs at a the frequency of 0.25 in population.
Introduction: The Hardy-Weinberg law states that in the absence of other evolutionary factors. the frequency of allele and genotypes or
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Chapter 19 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 19.8 - Why dont genetic markers on the Y chromosome...Ch. 19.8 - Prob. 2GRCh. 19 - If you suspected that heterozygous carriers of a...Ch. 19 - If allele frequencies in the hemoglobin gene are...Ch. 19 - Prob. 1QPCh. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - Prob. 4QPCh. 19 - Prob. 5QPCh. 19 - How Can We Measure Allele Frequencies in...
Ch. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - How Can We Measure Allele Frequencies in...Ch. 19 - Using the HardyWeinberg Law in Human Genetics...Ch. 19 - Prob. 10QPCh. 19 - Using the HardyWeinberg Law in Human Genetics In a...Ch. 19 - Prob. 12QPCh. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Prob. 15QPCh. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Prob. 17QPCh. 19 - Prob. 18QPCh. 19 - Measuring Genetic Diversity in Human Populations...Ch. 19 - Natural Selection Affects the Frequency of Genetic...Ch. 19 - Prob. 21QPCh. 19 - Prob. 22QPCh. 19 - The Evolutionary History and Spread of Our Species...Ch. 19 - Prob. 24QPCh. 19 - Genomics and Human Evolution The Denisovan genome...
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- Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic frequencies of the MN blood group locus (see Question 2 for a description of the MN blood group) in a small human population. You find that for 1-year-old children, the genotypic frequencies are MM = 0.25, MN = 0.5, and NN = 0.25, whereas the genotypic frequencies for adults are MM = 0.3, MN = 0.4, and NN = 0.3. a. Compute the M and N allele frequencies for 1-year-olds and adults. b. Are the allele frequencies in equilibrium in this population? c. Are the genotypic frequencies in equilibrium?arrow_forwardApplying Hardy-Weinberg equilibrium. For instance, a trait is caused by the homozygous state of a gene that is recessive and autosomal. 9% of individuals are expressing the phenotype. What is the percentage of individuals that are heterozygous?arrow_forwardUsing the example of pea color in Mendel’s pea plants, can you devise equations to determine the allele frequencies of A and a from the genotype frequencies of aa, Aa, and AA?arrow_forward
- Whether or not a person has cheek dimples is an autosomally inherited character due to variation in a single gene. Having cheek dimples (D) is dominant to not having cheek dimple s (d).In a population of 28,000 Greek children, 3,500 had cheek dimples and the rest did not. Assuming that the population is in Hardy-Weinberg equilibrium, A. what are the frequencies of the two alleles? B. how many of the children do you expect to be heterozygous?arrow_forwardIn a population of 1000 individuals, 180 have kinky hair, 360 have wavy hairy, and the rest have straight hair. Let us assume that hair type is governed by a pair of alleles, and there are two types of alleles, S (kinky) and s (straight), with the heterozygote condition being wavy. Compute for the allelic frequencies for hair type in the population.arrow_forwardFrom the pedigree shown here, answer the following questions with regard to individual VII-1. A. Who are the common ancestors of her parents? B. What is the inbreeding coefficient for this individual?arrow_forward
- For a gene existing in two alleles, what are the allele frequencies when the heterozygote frequency is at its maximum value, assuming Hardy-Weinberg equilibrium? What if there are three alleles?arrow_forwardConsider a rare deleterious recessive allele for a specific gene/locus. In this hypothetical population, the deleterious recessive allele exists at a proportion of 0.01. In an offspring with randomly chosen parents, what is the probability that the offspring will be homozygous for the deleterious recessive allele [q]?arrow_forwardApplying the Hardy-Weinberg equilibrium. 81% of the individuals are homozygous for a recessive allele. What percentage of the individuals would be expected to be heterozygous for this locus in the next generation?arrow_forward
- While traits Mendel worked with all adhered to his principles of inheritance, this is not the norm because phenotypes are typically a combination of both genetic and what other kind of influence?arrow_forwardAlkaptonuria is a recessive autosomal genetic disorder associated with darkening of the urine. In the United States, approximately 1 out of every 250,000people has alkaptonuria.a. Assuming Hardy-Weinberg equilibrium, estimatethe frequency of the allele responsible for this trait.b. What proportion of people in the U.S. populationare carriers for this trait? In this population, whatis the ratio of carriers to individuals affected byalkaptonuria?c. If a woman without alkaptonuria had a child withthis trait with one husband then remarried, what isthe chance that a child produced by her secondmarriage would have alkaptonuria?d. Alkaptonuria is a relatively benign condition, sothere is little selective advantage to individualswith any genotype; as a result, your assumptionof Hardy-Weinberg equilibrium in part (a) is reasonable. Could you also use the assumption ofHardy-Weinberg equilibrium to estimate the allelefrequencies and carrier frequencies of more severerecessive autosomal conditions…arrow_forwardWhat evolutionary factors can cause allele frequencies to change and possibly lead to a genetic polymorphism? Discuss the relative importance of each type of process.arrow_forward
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