Concept explainers
(a)
Interpretation:
If the given compound must be synthesized using compounds with six or fewer carbons, it is to be determined which carbon–carbon bond-forming reaction from Table 19-1 should be incorporated in the synthesis.
Concept introduction:
The carbon–carbon bond-forming reaction results in heteroatoms having a specific relative positioning along the carbon backbone. If the heteroatoms in a target have 1, 2-, 1, 3-, 1, 4-, or 1, 5- relative positioning and the synthesis calls for a carbon–carbon bond-forming reaction, then consider using a corresponding reaction from Table 19-1. In a retrosynthetic analysis, therefore, apply a transform that takes our target molecule back to reactants. Disconnect the appropriate C-C bond to take back to reactants.
(b)
Interpretation:
If the given compound must be synthesized using compounds with six or fewer carbons, it is to be determined which carbon–carbon bond-forming reaction from Table 19-1 should be incorporated in the synthesis.
Concept introduction:
The carbon–carbon bond-forming reaction results in heteroatoms having a specific relative positioning along the carbon backbone. If the heteroatoms in a target have 1, 2-, 1, 3-, 1, 4-, or 1, 5- relative positioning and the synthesis calls for a carbon–carbon bond-forming reaction, then consider using a corresponding reaction from Table 19-1. In a retrosynthetic analysis, therefore, apply a transform that takes our target molecule back to reactants. Disconnect the appropriate C-C bond to take back to reactants.
(c)
Interpretation:
If the given compound must be synthesized using compounds with six or fewer carbons, it is to be determined which carbon–carbon bond-forming reaction from Table 19-1 should be incorporated in the synthesis.
Concept introduction:
The carbon–carbon bond-forming reaction results in heteroatoms having a specific relative positioning along the carbon backbone. If the heteroatoms in a target have 1, 2-, 1, 3-, 1, 4-, or 1, 5- relative positioning and the synthesis calls for a carbon–carbon bond-forming reaction, then consider using a corresponding reaction from Table 19-1. In a retrosynthetic analysis, therefore, apply a transform that takes our target molecule back to reactants. Disconnect the appropriate C-C bond to take back to reactants.
(d)
Interpretation:
If the given compound must be synthesized using compounds with six or fewer carbons, it is to be determined which carbon–carbon bond-forming reaction from Table 19-1 should be incorporated in the synthesis.
Concept introduction:
The carbon–carbon bond-forming reaction results in heteroatoms having a specific relative positioning along the carbon backbone. If the heteroatoms in a target have 1, 2-, 1, 3-, 1, 4-, or 1, 5- relative positioning and the synthesis calls for a carbon–carbon bond-forming reaction, then consider using a corresponding reaction from Table 19-1. In a retrosynthetic analysis, therefore, apply a transform that takes our target molecule back to reactants. Disconnect the appropriate C-C bond to take back to reactants.
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ORGANIC CHEMISTRY SMARTWORK5 - ACCESS
- 9. On each of the structures shown below mark with an arrow where electrophilic aromatic substitution would take place. CN SO3H OH NO₂arrow_forwardTROVIOW Topicaj (References) Draw the major organic product of the reaction shown below. HO, NANH2 You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Include cationic counter-ions, e.g., Na" in your answer, but draw them in their own sketcher. (Review Top Draw the major organic product of the reaction shown below. OH K2Cr207 H2SO4, H20 • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • In cases where there is more than one answer, just draw one.arrow_forwardCurved arrows are used to illustrate the flow of electrons. Using the provided starting and product structures, draw the curved electron-pushing arrows for the following reaction or mechanistic steps. Be sure to account for all bond-breaking and bond-making steps. а :0: Select to Add Arrows THF H3O+ :OH: Mg H :O: Select to Add Arrows ga | Mg H Br Н' H H :O:arrow_forward
- Curved arrows are used to illustrate the flow of electrons. Using the provided starting and product structures, draw the curved electron-pushing arrows for the following reaction or mechanistic steps. Be sure to account for all bond-breaking and bond-making steps. يتو H:CE HH Select to Add Arrows H₂O H heat H Please select a drawing or reagent from the question areaarrow_forwardCurved arrows are used to illustrate the flow of electrons. Using the provided starting and product structures, draw the curved electron-pushing arrows for the following reaction or mechanistic step(s). Be sure to account for all bond- breaking and bond-making steps. Select to Add Arrows Br Select to Add Arrows :Br: لا :Br: - : م) :Br:Oarrow_forwardCurved arrows are used to illustrate the flow of electrons. Using the provided starting and product structures, draw the curved electron-pushing arrows for the following reaction or mechanistic steps. Be sure to account for all bond-breaking and bond-making steps. :O: :O: :O: H H Select to Add Arrows المال H I :0: Q NH3 > I I H Xi :0: H Select to Add Arrows ON H NH3 :0: ست H H Select to Add Arrows Problem 9 of 12 Please select a drawing or reagent from the question area Submitarrow_forward
- 2. Write the major products, if any, of each of the following reactions (please draw molecular structures, not just molecular formulas).arrow_forwardWhich reaction or statement regarding nucleophilic substitutions is incorrect? A) C₁ + 2 H2O ноттон + 2 HCI B) ta CI+MeOH to + HCI C) D) The rate-limiting step in SN1 reactions is the initial step, loss of the leaving group. Nucleophilic substitution reactions that follow second-order kinetics involve complete inversion of configuration.arrow_forwardivatives: Nucleophilic Acyl Substitution Reactions - EOC [References] From the table of available reagents select the one(s) you would use to convert butanoic acid to each of the following products: (Use the minimum number of steps; from one to six are required. List reagents by letter in the order that they are used; example: fa. NOTE: Assume that a normal aqueous (or mild acid) workup follows each reaction; you do not need to add reagents for the workup.) Reagents Available a. benzene/AlCl3 d. H2O, H2SO4 g. LiAlH4 j. PBг3 b. (CH3)2CuLi e. H₂, Pd/C h. NaCN C. CH3NH2 f. K* -OC(CH3)3 i. NH3 k. Dess-Martin periodinane I. SOCI₂ 1-butanol butanenitrilearrow_forward
- Provide the major organic product of the reaction shown. Na₂Cr₂O7, H₂SO4 'OH Draw the molecule on the canvas by choosing buttons from the Tools (for bonds), Atoms, and Advanced Template toolbars. The single bond is active by default.arrow_forwardCurved arrows are used to illustrate the flow of electrons. Using the provided starting and product structures, draw the curved electron-pushing arrows for the following reaction or mechanistic steps. Be sure to account for all bond-breaking and bond-making steps. 1 I I I Mg 0: Select to Add Arrows :O: Br: H CO2 THE :O: :0: Mg •87: Problem 11 of 20 Please select a drawing or reagent from the question area Submitarrow_forwardBased on the images attached, choose the alkene product formed for the following reaction and predict the major and minor compounds.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage LearningOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning