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To explain: The benefits of new information on the extent of genetic polymorphism among humans, particularly with respect to single-
Introduction: Variation that takes place in a single nucleotide in the genome can be termed as single-nucleotide polymorphism. The change in a single nucleotide can result in the development of diseases like sickle cell anaemia, cystic fibrosis, and so on. Copy number variation is the repetition of part of a genome.
To explain: The challenges of new information on the extent of genetic polymorphism among humans, particularly with respect to single-nucleotide polymorphism and copy number variation.
Introduction: Variation that takes place in a single nucleotide in the genome can be termed as single-nucleotide polymorphism. The change in a single nucleotide can result in the development of diseases like sickle cell anaemia, cystic fibrosis, and so on. Copy number variation is the repetition of part of a genome.
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Biology (MindTap Course List)
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- What evolutionary factors can cause allele frequencies to change and possibly lead to a genetic polymorphism? Discuss the relative importance of each type of process.arrow_forwardWhat historical, social, religious, cultural, and economic factors promote genetic drift in humans? Can you think of some specific human groups in which genetic drift is likely to have occurred?arrow_forwardPopulation bottlenecks are evident today in Arab communities, Israel, India, Thailand, Scandinavia, some African nations, and especially among indigenous peoples such as Native Americans. Research an indigenous or isolated population and describe a genetic condition that its members have that is rare among other groups of people, and how the population bottleneck occurred.arrow_forward
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- Looking to the future, what changes to the frequency of the sickle-cell allele do you envision as most likely, and why? (In other words, do you envision it becoming more common or less common in human populations?) What factors (technology, climate change, etc) might be driving those changes?arrow_forwardGeneticists study mitochondrial and Y-chromosome DNA to determine the ancestry of modern humans. Such studies have led to the emergence of mitochondrial Eve and Y-chromosome Adam, whose features above are a far-cry from an artist's interpretation of the Biblical narrative. Their progeny came to have the range of physical features now described as racial differences. How has modern genomics contributed to the debate about the validity and definition of these hypothetical parents and their descendants?arrow_forwardConnection to Quantitative traits: SNPs are inherited in a Mendelian fashion and are often polygenic in nature. We can think of SNPs in terms of either contributing or non-contributing alleles. A study of SNPs correlated with heart disease has shown that heart problems are severe if 9 or more of the alleles at 6 loci are of the contributing variety. What is the probability the following parents will have a child that is susceptible heart disease? AaBbccDDEEFf x AaBbCCDdEeffarrow_forward
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