EBK CONCEPTS OF GENETICS
EBK CONCEPTS OF GENETICS
12th Edition
ISBN: 9780134818979
Author: Killian
Publisher: YUZU
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Chapter 19, Problem 23ESP

(a)

Summary Introduction

To determine: The charge category of lysine.

Introduction: Lysine can be defined as an amino acid that is essential for the biosynthesis process of proteins. Lysine also has many other applications in the field of medicine.

(b)

Summary Introduction

To determine: The property of lysine that enables it to interact with the DNA.

Introduction: The DNA or the deoxyribonucleic acid is composed of nucleotides, and it comprises genetic information that is essential for development, and reproduction of organisms.

(c)

Summary Introduction

To determine: The effect of acetylation on lysine interaction with the DNA and gene expression activation.

Introduction: The process of acetylation is a chemical reaction. The addition of an acetyl group into a compound is defined as the process of acetylation. The reverse of this reaction is deacetylation.

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Q) a) A protein gains a mutation of a surface exposed residue. The mutation is Arg --> Leu. Based on the sequence of the protein when it folds the Leu remains on the surface of the protein. What is the change in chemical characteristic of the amino acid caused by this mutation? b) Briefly explain any entropic consequences of this mutation. (2 sentences MAX) c) What might happen in order to overcome these entropic consequences and how would that affect the cell? (1-2 sentences)
Suppose that a DNA segment has the following nucleotide sequence: CTC ATA CGA TTC AAG TTA. Which of the following nucleotide sequences would be found in a complementary mRNA strand? (a) GAG UAU GAU AAC UUG AAU. (b) GAG TAT GCT AAG TTC AAT. (c) GAG UAU GCU AAG UUC AAU. (d) GUG UAU GGA UUG AAC GGU.
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