CUSTOM BIOLOGY
19th Edition
ISBN: 9781323945490
Author: Urry
Publisher: Pearson Custom Publishing
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Chapter 19.2, Problem 3CC
Summary Introduction
To propose a hypothesis: To compare viral and cellular RNA polymerase in terms of template and functions.
Concept introduction: Cellular RNA polymerase is an enzyme found in all organisms. Viral RNA polymerases play an important role in replication and transcription of virus. Replication is a process of synthesizing an exact copy from the parent or template strand. Transcription is a process where RNA is formed using DNA or RNA as a template.
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You are studying a new retrovirus. The viral protein (X) appears to play a role in the export of the viral genomes to the
cytoplasm. Protein X brings viral DNA to the cytoplasm and returns back to the nucleus after genome export is complete.
Researchers have developed a new drug for the virus. Following treatment with the new drug, the viral protein stays in the
nucleus and cannot export the viral genomes. What is the most plausible and logical function of the drug? Use your
knowledge of nuclear transport to answer this question.
O A. The drug inhibits the binding of the viral protein and the viral genomes to the import receptor.
B. The drug inhibits the binding of Ran-GTP to the nuclear export receptor in nucleus.
C. The drug promotes the Ran GAP activity.
D. The drug blocks the NLS on the viral protein.
Assume you isolate a single stranded (+) RNA virus. When you examine the proteins in the virus, you find that it does NOT contain replicase enzymes within its capsid. Which of the following is true?
This virus must have a gene that encodes replicase.
This virus will not be able to enter a host cell.
Its genome cannot be translated (the process of translation) by the host cell ribosomes.
A DNA copy of the viral genome has to be made before viral genes are expressed.
This virus must lack surface antigens.
Viruses with negative sense RNA genomes typically, make proteins by: (Ignore retroviruses, and the unusual characteristics of coronaviruses)
Translation of short RNA transcripts generated by RDRP
Generating a DNA copy, which is then transcribed by host RNA polymerase.
Translation of the viral genome by host ribosomes.
Production of a polyprotein, which must be cleaved into smaller proteins.
Generating a negative sense genome copy, which is then translated by host ribosomes.
Chapter 19 Solutions
CUSTOM BIOLOGY
Ch. 19.1 - Prob. 1CCCh. 19.1 - Prob. 2CCCh. 19.2 - Compare the effect on the host cell of a lytic...Ch. 19.2 - MAKE CONNECTIONS Compare the CRISPR-Cas system to...Ch. 19.2 - Prob. 3CCCh. 19.2 - Why is HIV called a retrovirus?Ch. 19.2 - Prob. 5CCCh. 19.3 - Describe two ways in which a preexisting virus can...Ch. 19.3 - Contrast horizontal and vertical transmission of...Ch. 19.3 - WHAT IF? TMV has been isolated from virtually all...
Ch. 19 - Are viruses generally considered living or...Ch. 19 - Prob. 19.2CRCh. 19 - Prob. 19.3CRCh. 19 - Which of the following characteristics,...Ch. 19 - Emerging viruses arise by (A) mutation of existing...Ch. 19 - Prob. 3TYUCh. 19 - Prob. 4TYUCh. 19 - Prob. 5TYUCh. 19 - DRAW IT Redraw Figure 19.8 to show the replicative...Ch. 19 - EVOLUTION CONNECTION The successof some viruses...Ch. 19 - SCIENTIFIC INQUIRY When bacteria infect an animal,...Ch. 19 - WRITE ABOUT A THEME: ORGANIZATION While viruses...Ch. 19 - Prob. 10TYU
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