Concept explainers
(a)
Interpretation:
The preparation of the below given compound using directed aldol reactions has to be given.
Concept Introduction:
In directed aldol reactions, the enolate anion is prepared with one carbonyl compound by LDA (Lithium diisopropylamide). The other carbonyl compound acts as an electrophile. Both of the carbonyl compounds have α-hydrogens, but only one enolate is prepared using LDA. When unsymmetrical ketone is used, it forms less substituted enolate.
LDA (Lithium diisopropylamide) is a strong base. It converts
(b)
Interpretation:
The preparation of the below given compound using directed aldol reactions has to be given.
Concept Introduction:
In directed aldol reactions, the enolate anion is prepared with one carbonyl compound by LDA (Lithium diisopropylamide). The other carbonyl compound acts as an electrophile. Both of the carbonyl compounds have α-hydrogens, but only one enolate is prepared using LDA. When unsymmetrical ketone is used, it forms less substituted enolate.
LDA (Lithium diisopropylamide) is a strong base. It converts aldehydes, ketones and esters into their enolate anions.
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Chapter 19 Solutions
Organic Chemistry
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