Essentials of Genetics Plus Mastering Genetics with eText -- Access Card Package (9th Edition) (Klug et al. Genetics Series)
Essentials of Genetics Plus Mastering Genetics with eText -- Access Card Package (9th Edition) (Klug et al. Genetics Series)
9th Edition
ISBN: 9780134047201
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 2, Problem 3CS

CASE STUDY | Timing is everything

A man in his early 20s received chemotherapy and radiotherapy as treatment every 60 days for Hodgkin disease. After unsuccessful attempts to have children, he had his sperm examined at a fertility clinic, upon which multiple chromosomal irregularities were discovered. When examined within 5 days of a treatment, extra chromosomes were often present or one or more chromosomes were completely absent. However, such irregularities were not observed at day 38 or thereafter.

What is the obvious advice that the man received regarding fertility while he remained under treatment?

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1. A recently discovered bird species was found to have 29 chromosomes in its somatic cells before S phase. a. How many chromosomes (2n) are present in a somatic cell during mitosis? b. How many chromosomes does a bird receive from one parent? c. How many sister chromatids are present during metaphase 2? d. Assuming this species follows the same XX/XY sex differentiation as mammals, how many sex chromosomes are in an unfertilized egg? e. How many pairs of homologous chromosomes would you expect to see lined up during metaphase 2? 2. An onion cell (2n) with 10 autosomes and 2 sex chromosomes is about to undergo meiosis. How many cells will result from this process, and what is the chromosome number and ploidy of each cell?  3. An animal is heterozygous for two autosomal genetic traits found on different chromosomes. Purple fur is inherited dominantly (with pp genotype giving green fur) and the gene is located near the telomere on the short arm of an acrocentric autosome. The gene for…

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Essentials of Genetics Plus Mastering Genetics with eText -- Access Card Package (9th Edition) (Klug et al. Genetics Series)

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