(a)
Interpretation:
The reagent has to be proposed for the conversion of A to B.
Concept introduction:
Michael reaction:
The nucleophile is reaction with α,β-unsaturated carbonyl compound (1,4 –addtion) which yield the addition product is called Michael reaction.
(b)
Interpretation:
The reagent has to be proposed for the conversion of B to C.
Concept introduction:
Reduction:
(c)
Interpretation:
The reagent has to be proposed for the conversion of C to D.
Concept introduction:
Chlorination: Alcohols reaction with thionyl chloride gives chlorinated compound.
(d)
Interpretation:
The mechanism has to be proposed for the conversion of E to F and the formation of methyl chloride has to be shown through mechanism.
(e)
Interpretation:
The reagent has to be proposed for the conversion of F to Fluoxetine.
Concept introduction:
Hydrolysis: Amide undergoes hydrolysis using base like sodium hydroxide gives acid.
(f)
Interpretation:
The possible stereoisomer’s has to be shown if the product is chiral.
Concept introduction:
Chiral:
A molecule is non superimposable on its mirror image is called chiral molecule.
Four different atoms attached to a carbon atom is called chiral molecule.
Isomer: A molecule having the same molecular formula but with different chemical structure is called isomer.
Stereoisomers: Stereoisomers are molecules that have the same molecular formula and they differ only in arrangement of atom in three-dimensional space.
Enantiomers: A compound which is non-superimposable mirror image is called enantiomers.
Diastereomers: A compound which is non-superimposable and non-mirror image is called diastereomers.
Racemic mixture: A racemic mixture is simply a mixture containing an equal amount of each enantiomer.
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning