Essentials of Genetics Plus Mastering Genetics with eText -- Access Card Package (9th Edition) (Klug et al. Genetics Series)
9th Edition
ISBN: 9780134047201
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 21, Problem 2PDQ
Review the Chapter Concepts list on page 422. These all center on quantitative inheritance and the study and analysis of polygenic traits. Write a short essay that discusses the difference between the more traditional Mendelian and Neomendelian modes of inheritance (qualitative inheritance) and quantitative inheritance.
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Chapter 21 Solutions
Essentials of Genetics Plus Mastering Genetics with eText -- Access Card Package (9th Edition) (Klug et al. Genetics Series)
Ch. 21 -
CASE STUDY | A genetic flip of the coin
On July...Ch. 21 - CASE STUDY|A genetic flip of the coin On July 11,...Ch. 21 -
CASE STUDY|A genetic flip of the coin
On July...Ch. 21 - HOW DO WE KNOW?
1. In this chapter, we focused on...Ch. 21 - Review the Chapter Concepts list on page 422....Ch. 21 -
3. Define the following: (a) polygenic, (b)...Ch. 21 - A dark-red strain and a white strain of wheat are...Ch. 21 - Height in humans depends on the additive action of...Ch. 21 -
6. An inbred strain of plants has a mean height...Ch. 21 - Prob. 7PDQ
Ch. 21 - In the following table, average differences of...Ch. 21 - What kind of heritability estimates (broad sense...Ch. 21 - List as many human traits as you can that are...Ch. 21 - Corn plants from a test plot are measured, and the...Ch. 21 -
12. The following variances were calculated for...Ch. 21 - The mean and variance of plant height of two...Ch. 21 - A hypothetical study investigated the vitamin A...Ch. 21 - In a herd of dairy cows the narrow-sense...Ch. 21 - In an assessment of learning in Drosophila, flies...Ch. 21 - Suppose you want to develop a population of...Ch. 21 -
18. In a population of tomato plants, mean fruit...Ch. 21 - In a population of 100 inbred, genotypically...Ch. 21 - In a cross between a strain of large guinea pigs...Ch. 21 - While most quantitative traits display continuous...
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- Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you decide to have a child if the test results said that you carry the mutation for breast and ovarian cancer? The heart disease mutation? The TSD mutation? The heart disease and the mutant alleles?arrow_forwardPedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?arrow_forwardPedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?arrow_forward
- Provide a proof that a different phenotype can be produced from the same genotype. What are the possible causes for this different expression? How can the different gene interactions be differentiated from each other and from the Mendelian inheritance?arrow_forwardDiscuss how polygenic inheritance makes possible manyvariations of a trait.arrow_forwardWhat findings led geneticists to postulate the multiple- factor hypothesis that invoked the idea of additive alleles to explain inheritance patterns?arrow_forward
- Please define the following terms: Gene Allele Dominant Recessive Homozygous Heterozygousarrow_forwardSkin color is one of the traits in a human which is determined by polygenic inheritance system because it is possibly involving as many as 9 genes. To make this simple, let us consider the influence of 2 genes: A and B., where dark skin color is dominant. Suppose a man who is AABb marries a woman who is Aabb, what would be the genotypes of their children. Prove your answer by using a Punnet Square.arrow_forwardCompare and contrast non-mendelian inheritance in human traitsarrow_forward
- Explain the following features of the Mendelian traits and fill the Punnet Squares. a)The disappearance of recessive phenotype in the F1 generation. b)The genotype of an individual expressing dominant phenotype can be differentiated by the test cross.arrow_forwardBelow is a pedigree of a human genetic disease in which solid color indicates affected individuals. Assume that the disease is caused by a gene that can have the alleles A or a. a) Based on this pedigree, what is the most likely mode of inheritance? b) What is/are the possible genotype/s of person 1? c) What is/are the possible genotype (s) of person 4 ? Explain your answers.arrow_forwardWhat is the pattern of inheritance? Please Provide a specific reason that justifies your selection of this pattern of inheritance as the correct one, and also explain why each of the other two alternatives are not correct. As part of your answer, you must include the phenotypic ratio, including the sex of the offspring, that you would expect to find in each of the three possible scenarios. Please specify whether this pattren of inheritance is (i) rare X-linked recessive, (ii) sex-influenced, or (iii) sex-limited.arrow_forward
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