To predict: The locations of 14C in orotate isolated from cells grown on a small amount of uniformly labeled [14C].
Introduction:
The biosynthesis of pyrimidine is very simpler process than the purine. Synthesis of pyrimidine is a de novo synthesis pathway which involves six step reactions. During the process of biosynthesis six members ring of pyrimidine is made first and then it attached to ribose-5-monophosphate. The end product of this reaction is the Uridine-5-monophophate (UMP).
To justify: The prediction of the locations of 14C in orotate isolated from cells grown on a small amount of uniformly labeled [14C].
Introduction:
The biosynthesis of pyrimidine is very simpler process than the purine. Synthesis of pyrimidine is a de novo synthesis pathway which involves six step reactions. During the process of biosynthesis six members ring of pyrimidine is made first and then it attached to ribose-5-monophosphate. The end product of this reaction is the Uridine-5-monophophate (UMP).
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Lehninger Principles of Biochemistry (Instructor's)
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