ESSENTIALS OF GENETICS-W/MOD.ACCESS
9th Edition
ISBN: 9780134452876
Author: KLUG
Publisher: PEARSON
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Chapter 22, Problem 14PDQ
Assume that a recessive autosomal disorder occurs in 1 of 10,000 individuals (0.0001) in the general population and that in this population about 2 percent (0.02) of the individuals are carriers for the disorder. Estimate the probability of this disorder occurring in the offspring of a marriage between first cousins. Compare this probability to the population at large.
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Chapter 22 Solutions
ESSENTIALS OF GENETICS-W/MOD.ACCESS
Ch. 22 - CASE STUDY |An unexpected outcome A newborn...Ch. 22 - CASE STUDY |Anunexpected outcome A newborn...Ch. 22 - CASE STUDY|An unexpected outcome A newborn...Ch. 22 - HOW DO WE KNOW? Population geneticists study...Ch. 22 - Review the Chapter Concepts on page 441. All these...Ch. 22 -
3. Price et al. (1999. J. Bacteriol. 181:...Ch. 22 -
4. The genetic difference between two Drosophila...Ch. 22 - The use of nucleotide sequence data to measure...Ch. 22 - Calculate the frequencies of the AA, Aa, and aa...Ch. 22 - Prob. 7PDQ
Ch. 22 -
8. What must be assumed in order to validate the...Ch. 22 - In a population where only the total number of...Ch. 22 -
10. If 4 percent of a population in equilibrium...Ch. 22 -
11. Consider a population in which the frequency...Ch. 22 - If the initial allele frequencies are p = 0.5 and...Ch. 22 -
13. Under what circumstances might a lethal...Ch. 22 - Assume that a recessive autosomal disorder occurs...Ch. 22 -
15. One of the first Mendelian traits identified...Ch. 22 -
16. Describe how populations with substantial...Ch. 22 - Achondroplasia is a dominant trait that causes a...Ch. 22 -
18. A recent study examining the mutation rates...Ch. 22 - A form of dwarfism known as Ellis–van Creveld...Ch. 22 -
20. List the barriers that prevent interbreeding...Ch. 22 - What are the two groups of reproductive isolating...Ch. 22 - Prob. 22PDQCh. 22 -
23. In a recent study of cichlid fish inhabiting...Ch. 22 - What genetic changes take place during speciation?Ch. 22 - Some critics have warned that the use of gene...Ch. 22 - Comparisons of Neanderthal mitochondrial DNA with...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- In Sweden 1/500 are born with an autosomal recessive disorder called thalassemia. What is the carrier frequency within the population?arrow_forwardIf the frequency of a homozygous recessive disorder is 1 in 10,000, the frequency of the dominant allele is ________ % and the heterozygous genotype frequency is ________ %.arrow_forwardSuppose that two parents are both heterozygous for sickle cell anemia, which is an autosomal recessive disease. They have seven children. Use the binomial theorem to determine the probability that three of the children have sickle cell anemia and four children are healthy. Round your answer to the nearest hundredtharrow_forward
- If 98 out of 200 individuals in a population express the recessive phenotype, what percent of the population are heterozygotes? Show a clear solution.arrow_forwardTay–Sachs disease is an autosomal recessive disorder. AmongAshkenazi Jews, the frequency of Tay–Sachs disease is 1 in 3600. If theAshkenazi population is mating randomly with respect to the Tay–Sachsgene, what proportion of the population consists of heterozygouscarriers of the Tay–Sachs allele?arrow_forwardIf a trait determined by an autosomal recessive allele occurs at a frequency of 0.25 in a population, what are the the allelic frequencies? Assume Hardy-Weinberg equilibrium and use A and a to symbolize the dominant and recessive alleles, respectively.arrow_forward
- Cystic fibrosis is a genetic disease mostly affecting people of European descent that is caused by a recessive allele. You sample 1000 people for this allele and find 772 homozygous normal individuals, 221 heterozygotes, and 7 people homozygous for cystic fibrosis. Is this population in Hardy-Weinberg equilibrium?arrow_forwardIf a particular population of diploid individuals is in equilibrium and contains 16% homozygous dominant individuals, 48% heterozygotes, and 36% homozygous recessive individuals, what is the frequency of the recessive allele in this population?arrow_forwardIf the frequency of those homozygous for a rare clinically relevant allele that causes an autosomal monogenic recessive condition in a given population of 15 million individuals is 1/8500, how many individuals are likely to be carriers of the causative mutation? Please give your answer as a whole number.arrow_forward
- How does a heterozygous organisms differ from a homozygous organism in terms of the alleles they contribute to the population? Provide your best explanation for the law of segregation in 1-2 sentences.arrow_forwardAssume that a recessive autosomal disorder occurs in 1 of 10,000 individuals (0.0001) in the general population and that in this population about 2 percent (0.02) of the individuals are carriers for the disorder. Estimate the probability of this disorder occurring in the offspring of a marriage between first cousins. Compare this probability to the population at large.arrow_forwardConsider a population with 28 individuals with the genotype AA and 12 Aa individuals and 50 individuals with the genotype aa how many alleles in this population in total?arrow_forward
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