Biochemistry (Looseleaf)
9th Edition
ISBN: 9781319114800
Author: BERG
Publisher: MAC HIGHER
expand_more
expand_more
format_list_bulleted
Question
Chapter 22, Problem 32P
Interpretation Introduction
Interpretation:
The carbon atoms in palmitic acid that were donated by acetyl CoA should be determined.
Concept introduction:
The process of fatty acid synthesis occurs in the cytosol of the animal cells, while it occurs in the stroma of chloroplast in the plant cells. It is a stepwise process, which occurs by the addition of two-carbon units. These carbon units are provided by the acetyl-CoA, derived from glucose oxidation.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
In fatty acid synthesis, malonyl-CoA, rather thanacetyl-CoA, is used as a “condensing group.” Suggest a reason for this.
All of the following are accurate contrasts for beta oxidation vs fatty acid synthesis except which of the following statements?
Group of answer choices
The hydroxylacyl group differs in stereochemistry between beta oxidation and biosynthesis
CoA is the acyl carrier group in beta oxidation, acyl carrier protein is the carrier in biosynthesis
The carbon unit resulting from beta oxidation is acetyl-CoA, the carbon unit for biosynthesis is malonyl-CoA
FAD is an electron acceptor in beta oxidation, NADP+ is the electron acceptor in biosynthesis
HO.
Hexanoic acid is a 6-carbon saturated fatty acid found in goat's milk. Hexanoic acid also contributes to the "barnyard" smell of goats.
Fun fact: Hexanoic acid is also known as caproic acid. The name "caproic" is derived from the Latin word "caper", which means goat.
What is the balanced equation for complete beta oxidation of hexanoyl-COA to acetyl-CoA shown below (ignore H20 and H+):
O Hexanoyl-COA + 3COA + 3FAD + 3NAD+ -------> 3 acetyl-COA + 3 FADH2 +3 NADH
O Hexanoyl-CoA + 2COA + 2FAD + 2NAD+
--> 3 acetyl-CoA + 2 FADH2 + 2 NADH
O Hexanoyl-CoA + 1COA + 1FAD + 1NAD+
--> 2 acetyl-CoA + 1 FADH2 +1 NADH
O Hexanoyl-COA + 6COA + 6FAD + 6NAD+ --------> 6 acetyl-CoA.+ 6 FADH2 + 6 NADH
None of the above
Chapter 22 Solutions
Biochemistry (Looseleaf)
Ch. 22 - Prob. 1PCh. 22 - Prob. 2PCh. 22 - Prob. 3PCh. 22 - Prob. 4PCh. 22 - Prob. 5PCh. 22 - Prob. 6PCh. 22 - Prob. 7PCh. 22 - Prob. 8PCh. 22 - Prob. 9PCh. 22 - Prob. 10P
Ch. 22 - Prob. 11PCh. 22 - Prob. 12PCh. 22 - Prob. 13PCh. 22 - Prob. 14PCh. 22 - Prob. 15PCh. 22 - Prob. 16PCh. 22 - Prob. 17PCh. 22 - Prob. 18PCh. 22 - Prob. 19PCh. 22 - Prob. 20PCh. 22 - Prob. 21PCh. 22 - Prob. 22PCh. 22 - Prob. 23PCh. 22 - Prob. 24PCh. 22 - Prob. 25PCh. 22 - Prob. 26PCh. 22 - Prob. 27PCh. 22 - Prob. 28PCh. 22 - Prob. 29PCh. 22 - Prob. 30PCh. 22 - Prob. 31PCh. 22 - Prob. 32PCh. 22 - Prob. 33PCh. 22 - Prob. 34PCh. 22 - Prob. 35PCh. 22 - Prob. 36PCh. 22 - Prob. 37PCh. 22 - Prob. 38PCh. 22 - Prob. 39PCh. 22 - Prob. 40PCh. 22 - Prob. 41PCh. 22 - Prob. 42PCh. 22 - Prob. 43PCh. 22 - Prob. 44PCh. 22 - Prob. 45PCh. 22 - Prob. 46PCh. 22 - Prob. 47PCh. 22 - Prob. 48PCh. 22 - Prob. 49PCh. 22 - Prob. 50PCh. 22 - Prob. 51PCh. 22 - Prob. 52PCh. 22 - Prob. 53PCh. 22 - Prob. 54PCh. 22 - Prob. 55PCh. 22 - Prob. 56PCh. 22 - Prob. 57PCh. 22 - Prob. 58PCh. 22 - Prob. 59PCh. 22 - Prob. 60PCh. 22 - Prob. 61PCh. 22 - Prob. 62P
Knowledge Booster
Similar questions
- Only one acetyl CoA molecule is used directly in fatty acid synthesis. Identify the carbon atoms in palmitic acid that were donated by acetyl CoA.arrow_forwardPalmitoleic acid, 16:1Δ⁹ hexadecaenoic acid, (16 carbon FA with one double bond )is an important fatty acid component of TAGs and cell membranes. Briefly explain the process of beta oxidation of this fatty acid and the number (only) of FADH, NADH and acetyl CoA outcome. What is the total ATP (only number) generated from this fatty acid after beta oxidation.arrow_forwardPalmitic acid is a straight-chain saturated 16-carbon fatty acid. How many moles of malonyl-CoA are required for the synthesis of one mole of palmitic acid?arrow_forward
- How many tritium atoms (PH) are incorporated into palmitate when fatty acid synthesis is carried out in vitro with the following labeled substrate? -ooc-C°H,-C-s-CoAarrow_forward(i) Consider a preparation that contains all the enzymes and cofactors necessary for fatty acid biosynthesis from acetyl-CoA and malonyl-CoA. If [2-H] acetyl-CoA labeled with deuterium, the heavy isotope of hydrogen and excess of unlabeled malonyl-CoA are added as substrates, where will you find these labeled deuterium atoms in a molecule of palmitate synthesized? Explain. S-COA (ii) Describe the steps involved in the synthesis of palmitic acid starting from acetyl-CoA and malonyl-CoA.arrow_forwardLooking at the structure of alpha linolenic acid, how many rounds of beta oxidation will occur to fully oxidize the fatty acid into acetyl CoA molecules? Please provide explanationsarrow_forward
- Part A Identify each of the following metabolic pathways. Drag the appropriate labels to their respective targets. Reset Help the conversion of fatty acids to 2-carbon units of acetyl CoA ketogenesis the conversion of an amino acid to an a-keto transamination acid the combination of 2-carbon units of acetyl COA to form fatty acids oxidative deamination the removal of an amino group as NH4+ from B oxidation glutamate to yield a-ketoglutarate lipogenesis the production of ketone bodiesarrow_forwardDraw the product of the dehydration reaction of the B- hydroxyacyl-SACP catalyzed by B-hydroxyacyl-ACP dehydratase (DH) in the third elongation step of fatty acid synthesis. Provide the structure in the protonation state found in physiological conditions. OH B-hydroxyacyl-ACP dehydratase (DH) O Drawing SACP Qarrow_forwardWhich of the following is NOT part of the multi-enzyme complex of fatty acid synthase? O enoyl-ACP reductase O acetyl CoA carboxylase O 3-hydroxybutyrylACP-dehydratese O B-ketoacyl-ACP reductasearrow_forward
- What is(are) the only active site(s) not used in the second round of fatty acid synthase? Select all that apply. Group of answer choices Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP Reductasearrow_forwardOn these following choices, Malonyl CoA synthase, Malonyl CoA synthetase, Acetyl CoA carboxylase and Acetyl CoA decarboxylase, what is the correct answer in fatty acid synthesis?arrow_forwardHow many ATP can be produced by the complete oxidation of each propionyl-CoA product of fatty acid oxidation? Compare this to the ATP yield for each acetyl-CoA.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. Freeman
Lehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage Learning
BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Fundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON