(a)
Interpretation:
The reason for the requirement of ATP hydrolysis by the 26S proteasome should be determined.
Concept introduction:
Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.
(b)
Interpretation:
The reason for small peptides can be hydrolyzed deprived of the ATP use should be determined.
Concept introduction:
Proteasome is a composite of proteinases that are involved in the breakdown of specific intracellular proteins. ATP hydrolysis is a catabolic process that helps in releasing the chemical energy from the high-energy phosphoanhydride bonds in ATP. Energy is liberated by splitting these bonds.
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BIOCHEMISTRY-ACHIEVE (1 TERM)
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