Biochemistry
Biochemistry
8th Edition
ISBN: 9781464126109
Author: Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr., Lubert Stryer
Publisher: W. H. Freeman
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Chapter 23, Problem 6P
Interpretation Introduction

(a)

Interpretation:

The balanced equation involved in the transformation of aspartate into glucose through an intermediate oxaloacetatemolecule and coenzymes should be written.

Concept introduction:

Transamination is also known as an amino transfer. It is a chemical reaction that takes place between two molecules. One is an amino acid that contains an amine or -NH2 group and the other is a keto acid having a keto (=O) group.

Interpretation Introduction

(b)

Interpretation:

The balanced equation involved in the transformation of aspartate into oxaloacetate through an intermediate fumarate molecule should be written.

Concept introduction:

The urea cycle is a series of biochemical reactions which involve the formation of urea (NH2)2CO from the ammonia (NH3). It is also known as the ornithine cycle. It helps in the excretion of toxic ammonia by converting into urea. This cycle takes place in ureotelic organisms.

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Long explanations are not needed. Direct answers would suffice.   a. High concentration of glucose 6-phosphate is inhibitory to the enzyme hexokinase. I. True II. False   b. Which compound is formed when NAH reduces pyruvate (anaerobic condition)? I. lactate II. alpha-ketoglutarate III. glucose IV. oxaloacetate
G. ENZYME CLASSIFICATION. Identify the main class of enzymes used to catalyzed the following reactions: 1. Lactate dehydrogenase: NADH+H NAD HC-OH CH3 CH Pynnte Lactate 2. Methylmalonyl-CoA mutase: CH CH SCOA CH,CH, SCOA coenzyme B12 COO COO methylmalonyl-CoA succinyl-CoA 3. Enolase: 0. H–Ċ–0–P–0- C-0–P-0- + H,0 HO–CH, CH 6 Phosphoenolpyruvate 2-Phosphoglycerate 4. Chymotrypsin: -0–CH,CH3 + H2O - RCOOH + HOCH,CH3 5. Pyruvate carboxylase: coo • co, • ATP + H,0 H-C-H . ADP + P, + 2H čoo CH, Pyruvate Oxaleacetate
X INCORRECT; see section 13.1 Enzymes occasionally display weak "“side" activities. Draw the structure of the product (other than ADP) of the reaction that results when pyruvate kinase, operating in reverse, uses lactate as a substrate. For your structure: 1. Do not include primary or secondary hydrogens. CH2 HO OH Edit Drawing
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