Interpretation:
A mechanism for the first step in the Mannich reaction shown, a reaction between acetaldehyde and dimethyl
Concept introduction:
The steps involved in the formation of the iminium ion are i) Protonation of the
The reaction between iminium ion intermediate and cyclohexanone takes place through the following steps i) Reaction between the enol form of the cyclohexanone and iminium ion ii) Deprotonation of the intermediate.
To propose:
A mechanism for the first step in the Mannich reaction shown, a reaction between acetaldehyde and dimethyl amine, to yield an iminium ion intermediate along with water. To show the structure of the iminium ion intermediate.
Further to propose a mechanism for the second step involving the reaction between iminium ion intermediate and cyclohexanone.
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Chapter 23 Solutions
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning